Results 31 to 40 of about 88,730 (192)

Búsqueda de metástasis óseas en radiografías [PDF]

open access: yes, 2012
Some authors claim that it is impossible to detect early bone metástasis in flat x-rays. However, mainly due to its cost, it remains the first diagnostic tool for the disease and, when it cannot be observed, other techniques are employed.
ALBERTO JARAMILLO NUÑEZ   +1 more
core  

Deterioro cognitivo por metástasis cerebrales múltiples

open access: yes, 2019
Mujer de 84 años con antecedente de cáncer de pulmón con deterioro cognitivo de rápida evolución secundario a metástasis ...
Requeno Jarabo, Maria Nuria   +3 more
core   +1 more source

Efectos divergentes de la inhibición de TGF-ß en metástasis óseas de cáncer de mama y pulmón

open access: yesRevista de Osteoporosis y Metabolismo Mineral, 2013
Fundamento: El objetivo de este estudio radica en la determinación de la validez del factor de crecimiento transformante β (TGF-β) como diana terapéutica en modelos de metástasis óseas derivadas de distintos tipos histopatológicos del cáncer de pulmón.
Luis-Ravelo D   +7 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Tumor de células de Merkel

open access: yesRevista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2005
El carcinoma de células de Merkel es un tumor cutáneo, infrecuente, altamente agresivo, con gran tendencia a la diseminación regional y a distancia, que generalmente ocurre en la cabeza y el cuello de las personas ancianas.
Paula Mejía Z.   +2 more
doaj  

Cytotoxic activity of the chloroform fraction of Piper aduncum and its effect on the cell cycle in gastric cancer cell lines

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2020
Objectives: To evaluate the cytotoxic activity of the chloroform fraction of the Piper aduncum methanolic extract (PAMoCl) and its effect on the cell cycle in two gastric cancer cell lines: AGS and KATO III. Materials and methods: The cytotoxic effect of
Ana Mayanga-Herrera   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Metástasis musculares del adenocarcinoma renal [PDF]

open access: yes, 2011
The renal cell carcinoma can produce metastatic, the most common are in lung, liver, bones and encephalon. The isolated metastatic in muscle are unusual, there are only twenty cases published, most of them isolated cases.
Serrano, P.   +3 more
core  

Metástasis gástrica de tumor de células germinales mixto primario testicular: reporte de caso

open access: yesHorizonte Médico, 2022
Los tumores testiculares son raros; sin embargo, en la población masculina dentro del grupo etáreo de 15 a 29 años, el cáncer de testículo es el tumor sólido más común, siendo el tumor de células germinales del tipo no seminomatoso, el más frecuente.
Fernando Barreda Bolaños   +4 more
doaj   +1 more source

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