Non‐surgical management vs active treatment in T1a renal cell carcinoma: a population‐based study
BJU International, Volume 137, Issue 2, Page 297-305, February 2026.Objectives To compare overall and cancer‐specific survival for clinical (c)T1aN0M0 renal cell carcinoma (RCC) in patients treated with non‐surgical management (NSM: surveillance and watchful waiting) or active treatment (surgery and ablative treatments). Patients and methods In this nationwide real‐world population‐based cohort study, data on clinical,
Bassam Mazin Hashim +4 more
wiley +1 more source
“FRECUENCIA DE TUMORES DE APÉNDICE CECAL EN PACIENTES ADULTOS OPERADOS DE APENDICECTOMÍA EN EL HOSPITAL GENERAL DR. NICOLÁS SAN JUAN DE 2008 A 2013.” [PDF]
, 2014 Flores Morales, José Luis +2 more
core
WHO classification of skin tumours: key updates in the fifth edition
Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy +29 more
wiley +1 more source
An Uncharted Path of Metastasis: A Case Report of Sigmoid Colon Cancer with Synchronous Vaginal and Urethral Spread. [PDF]
DiseasesMontenegro JF +8 more
europepmc +1 more source
Molecular profile of atypical Leydig cell tumours
Histopathology, Volume 88, Issue 3, Page 628-635, February 2026.Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry +6 more
wiley +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
International Journal of Cancer, Volume 158, Issue 2, Page 342-356, 15 January 2026.Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
wiley +1 more source
ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role. [PDF]
World J Clin OncolPalacios Serrato EG +5 more
europepmc +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source