Results 161 to 170 of about 1,366,906 (203)
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Existence of Met-enkephalin-Arg6-Gly7-Leu8 with Met-enkephalin, Leu-enkephalin and Met-enkephalin-Arg6-Phe7 in the brain of guinea pig, rat and golden hamster

Biochemical and Biophysical Research Communications, 1982
Abstract High performance liquid chromatography (HPLC) coupled with specific radioimmunoassays for methionine-enkephalin-Arg6-Gly7-Leu8 (Met-E-Arg6-Gly7-Leu8), methionine-enkephalin (Met-E), leucine-enkephalin (Leu-E) and methionine-enkephalin-Arg6-Phe7 (Met-E-Arg6-Phe7) has demonstrated that Met-E-Arg6-Gly7-Leu8 exists together with Met-E, Leu-E and
Y, Ikeda   +5 more
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Effects of Met-enkephalin on the mechanical activity and distribution of Met-enkephalin-like immunoreactivity in the cat small intestine

Peptides, 1990
Naloxone-dependent effects of Met-enkephalin (10(-8) M) on the spontaneous and electrically induced mechanical activities were studied in longitudinal and circular preparations isolated from the cat duodenum, jejunum and ileum. Met-Enkephalin changed the spontaneous activity of all preparations tested with the exception of the circular preparations ...
R, Radomirov   +3 more
openaire   +2 more sources

Effects of Met-enkephalin on the mechanical activity and distribution of Met-enkephalin-like immunoreactivity in the cat large intestine

Peptides, 1992
The effects of Met-enkephalin on the spontaneous and electrically evoked activity were investigated in longitudinal and circular strips isolated from different regions of the large intestine, i.e., proximal colon, distal colon and rectum. Met-enkephalin induced dose-dependent contractile responses which were reversibly blocked by naloxone (10(-6) M ...
K, Venkova, M, Davidoff, R, Radomirov
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Uptake/internalization of met-enkephalin by brain synaptosomes

Life Sciences, 1983
In this manuscript, we provide evidence for the uptake of met-enkephalin by brain neurons. Tritiated met-enkephalin was accumulated by a crude synaptosomal fraction of rat brain, in the presence of peptidase inhibitors. Characterization of this process in striatum and mediobasal hypothalamus showed incubation time- and temperature-dependence and ...
G R, Van Loon, S R, George
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Plasma met-enkephalin in type I diabetes

Metabolism, 1992
Physiological and pathological evidence suggests that opioid peptides may play a role in glucose homeostasis. We measured plasma levels of beta-endorphin (beta-END) and met-enkephalin (met-ENK) in 22 type I diabetic patients and 15 healthy women (control group).
NEGRI M   +3 more
openaire   +3 more sources

INHIBITION OF THE ENZYMATIC DEGRADATION OF MET-ENKEPHALIN BY CATECHOLAMINES

Endocrinology, 1982
The influence of the catecholamine hormones and some of their metabolites on the enzymatic degradation of met-enkephalin by rat brain homogenates has been evaluated. The enzyme activity was determined by the release of [125I]-tyrosine from radioiodinated met-enkephalin following Porapak Q column chromatography.
J L, Caffrey, D H, Hodges
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In vivo release of met-enkephalin in the cat brain

Neuroscience, 1981
Abstract Push-pull cannulae were implanted into the globus pallidus (anterior part), the caudate nucleus (medio-dorsal part) and the substantia nigra of halothane-anaesthesized cats to study the characteristics of the in vivo release of met-enkephalin. Met-enkephalin was measured by radioimmunoassay (sensitivity: 0.1 pg) and identified by Bio-Gel P
F, Cesselin   +7 more
openaire   +2 more sources

Met-enkephalin effects on associations formed in utero

Peptides, 1982
Rat fetuses exposed to an odor stimulus and an aversive stimulus in utero showed an aversion to the odor when tested 16 days postnatally. Fetuses that also received 80 micrograms/kg Met-enkephalin showed a greater aversion to the odor stimulus than those subjects that did not receive the peptide.
G, Stickrod   +2 more
openaire   +2 more sources

A characterization of the in vivo immunomodulation by met-enkephalin in mice

International Journal of Immunopharmacology, 1993
Single intraperitoneal injections of Met-enkephalin (MENK) into CBA mice decreased the phagocytic activity of peritoneal macrophages, Con-A-induced proliferation and NK-activity of spleen cells. Conversely, in mice which had been immunized with sheep erythrocytes, treatment with MENK was associated with enhancement of phagocytosis, and no effect on ...
Rabatić, Sabina   +2 more
openaire   +2 more sources

Met-enkephalin stimulates secretion of ACTH in sheep

Journal of Endocrinology, 1986
ABSTRACT The ability of opioid peptides to affect plasma immunoreactive ACTH concentrations was examined in conscious sheep. Plasma concentrations of ACTH were significantly increased by an i.v. infusion of Met-enkephalin and its analogue (FK-33824).
X M, Wang   +4 more
openaire   +2 more sources

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