Results 151 to 160 of about 946,904 (210)
Smart Polymeric Nanocarriers of Met-enkephalin
Biomacromolecules, 2016 This study describes a novel approach to polymeric nanocarriers of the therapeutic peptide met-enkephalin based on the aggregation of thermoresponsive polymers. Thermoresponsive bioconjugate poly((di(ethylene glycol) monomethyl ether methacrylate)-ran-(oligo(ethylene glycol) monomethyl ether methacrylate) is synthesized by AGET ATRP using modified met ...
Roza, Szweda +8 more
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Met-enkephalin immunoreactivity in blood platelets
Life Sciences, 1982 Picogram amounts (50-150 pg/mg protein) of immunoreactive met-enkephalin material (met-enkephalin IR) were detected by radioimmunoassay in human, rat and rabbit platelets. Characterization of this material by thin-layer chromatography, gel filtration chromatography and high-pressure liquid chromatography indicated that it behaves identically with ...
A.M. Di Giulio +4 more
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Peptides, 1984
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
R Yoshiyuki Osamura, Takaaki Yoshimasa
exaly +3 more sources
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
R Yoshiyuki Osamura, Takaaki Yoshimasa
exaly +3 more sources
Radioimmunological and immunocytochemical demonstration of met-enkephalin in planaria
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1983 1. An anti-Met-enkephalin serum has been used for radioimmunological and immunocyto-chemical demonstration of Met-enkephalin in planaria. 2. The serum showed a high degree of sensitivity and specificity. 3. Radioimmunoassay demonstrated in planaria extracts a considerable concentration of Met-enkephalin. 4.
VENTURINI G +4 more
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Peptides, 1992
The effects of Met-enkephalin on the spontaneous and electrically evoked activity were investigated in longitudinal and circular strips isolated from different regions of the large intestine, i.e., proximal colon, distal colon and rectum. Met-enkephalin induced dose-dependent contractile responses which were reversibly blocked by naloxone (10(-6) M ...
K Venkova, M Davidoff, R Radomirov
exaly +3 more sources
The effects of Met-enkephalin on the spontaneous and electrically evoked activity were investigated in longitudinal and circular strips isolated from different regions of the large intestine, i.e., proximal colon, distal colon and rectum. Met-enkephalin induced dose-dependent contractile responses which were reversibly blocked by naloxone (10(-6) M ...
K Venkova, M Davidoff, R Radomirov
exaly +3 more sources
Immunomodulation by two potent analogs of met-enkephalin
Immunopharmacology, 1997 Met-enkephalin (Tyr-Gly-Gly-Phe-Met) and its more stable analogs, Tyr-D-Ala-Gly-MePhe-Met-NHC3H gamma-iso (1) and Tyr-D-Ala-Gly-MePhe-Gly-NHC3H gamma-iso (2) significantly enhanced human T-cell proliferation in vitro after 5 days of incubation in the absence of mitogen. The activity was completely inhibited by naloxone, an opioid antagonist.
K, Bajpai +5 more
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The assay of Met-enkephalin aminopeptidase with [125I]Met-enkephalin
Journal of Biochemical and Biophysical Methods, 1982Presented here are procedural modifications which permit the utilization of 125I-labeled Met-enkephalin as substrate in the assay of rat brain enkephalin aminopeptidase. Th hydrolysis of enkephalin is monitored by the release of [125I]tyrosine separated on Porapak Q.
J L, Caffrey, D H, Hodges
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Dual immunomodulation by met-enkephalin
Brain, Behavior, and Immunity, 1989Met-enkephalin (MENK) is an opioid peptide that is released during physiological stress and is reported to either up-regulate or down-regulate the immune response. Our previous experiments showed the ability of 10(-7) M MENK to modulate the plaque-forming cell (PFC) response of Mishell-Dutton cultures treated with low, optimal, and large concentrations
R R, Rowland, S, Tokuda
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