Results 151 to 160 of about 1,366,906 (203)

Interaction of met-enkephalin and corticosteroids in immunomodulation

International Journal of Immunopharmacology, 1992
The effect of Met-enkephalin (MENK) on several immune functions, corticosterone (CS) and adrenocorticotropin (ACTH) levels in the plasma was studied in adrenalectomized (ADX) and sham-adrenalectomized (SADX) mice. Multiple Met-enkephalin injections (10 mg/kg per day in two injections 12 h apart, for 4 days) increased the plaque-forming cell response to
Gabrilovac, Jelka, Ročić, Boris, Marotti, Tatjana, Haberstock-Debić, Helena   +3 more
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Met-enkephalin-arg6-gly7-leu8 exists together with met-enkephalin-arg6-phe7, met-enkephalin and leu-enkephalin in human stomach

Life Sciences, 1983
Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
M, Sakamoto, K, Nakao, T, Yoshimasa, Y, Ikeda, M, Suda, N, Yanaihara, H, Imura   +6 more
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Met-enkephalin receptors in human gliomas

NeuroReport, 1994
Endogenous opioid systems (opioid peptides and receptors) are involved in many functions including the regulation of cell growth. We investigated the presence of Met-enkephalin binding sites in gliomas by displacement assays. Results demonstrated that few gliomas exhibit Met-enkephalin binding sites and that the percentage of tumours which express ...
L, Molin, J M, Verna, M F, Nissou, A L, Benabid   +3 more
openaire   +2 more sources

Met-enkephalin circulates in human plasma

Nature, 1980
The physiological roles of Met-enkephalin and Leu-enkephalin are still unknown. They may act as neurotransmitters in the central and peripheral nervous systems. Met-enkephalin has been detected in several species in a variety of tissues including brain, spinal cord and gut using bioassays, opiate receptor assays and radioimmunoassays (RIA). It has also
V, Clement-Jones, P J, Lowry, L H, Rees, G M, Besser   +3 more
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Interaction of Met‐Enkephalin with Human Granulocytes

Annals of the New York Academy of Sciences, 1987
Met-enkephalin has been found to have an effect on cell shape and motility of human polymorphonuclear leukocytes (PMNs). Specific binding of tritium-labeled Met-enkephalin to the cells could not be demonstrated. There was a rapid proteolytic degradation of the peptide in the medium, followed by uptake of the labeled tyrosine.
E G, Fischer, N E, Falke
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Met-enkephalin-Arg6-Phe7 metabolism: Conversion to Met-enkephalin by brain and kidney dipeptidyl carboxypeptidases

Biochemical and Biophysical Research Communications, 1981
Abstract Enzymes degrading Met-enkephalin-Arg 6 -Phe 7 , an endogenous brain peptide with enhanced opiate activity in vivo, were isolated from membrane preparations of rabbit kidney and brain, and their specificity compared. A preparation from kidney or brain containing the angiotensin converting enzyme (EC 3.4.15.1) released with time Arg-Phe, Met ...
M, Benuck, M J, Berg, N, Marks
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Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin in human adrenal medulla and pheochromocytomas

Peptides, 1984
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
R Y, Osamura, K, Watanabe, T, Yoshimasa, K, Nakao, H, Imura   +4 more
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Met-Enkephalin in Oxidative Stress

2006
Hugo Besedovsky demonstrated immune-brain communications more than 35 years ago. His recent findings concern the ability of IL-1 (centrally mediated immune challenge) to induce hypoglycaemia (response of immune tissue on periphery). So we no longer question that injection of immune modulators can affect the brain or that the immune system can interfere
Haberstock-Debić, Helena, Marotti, Tatjana, Šverko, Ana-Višnja, Sobočanec, Sandra, Balog, Tihomir   +4 more
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Occurrence of met-enkephalin, met-enkephalin-Arg6-Phe7 and met-enkephalin-Arg6-Gly7-Leu8 in gastrin cells of hog antral mucosa

Cell and Tissue Research, 1985
Region-specific antisera to three enkephalins: met-enkephalin, met-enkephalin-Arg6-Phe7 and met-enkephalin-Arg6-Gly7-Leu8, together with four region specific antisera to progastrin: C-terminal G17 specific, N-terminal G34 specific, cryptic peptides A- and B-specific, were used in immunohistochemical studies of hog antral mucosa. A sub-population (6-10%)
openaire   +2 more sources

Enzymatic synthesis of Leu- and Met-enkephalin

Biochemical and Biophysical Research Communications, 1979
Abstract The protease-catalyzed synthesis of Leu- and Met-enkephalin is reported. Each peptide bond of the endogeneous opiate-pentapeptides was formed either by papain or α-chymotrypsin catalysis. N-acyl amino acids and peptides or their ester derivatives served as substrates whereas amino acid and peptide phenylhydrazides were used as nucleophiles ...
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