Results 131 to 140 of about 10,961 (170)

Effects of Met-enkephalin on the mechanical activity and distribution of Met-enkephalin-like immunoreactivity in the cat small intestine

Peptides, 1990
Naloxone-dependent effects of Met-enkephalin (10(-8) M) on the spontaneous and electrically induced mechanical activities were studied in longitudinal and circular preparations isolated from the cat duodenum, jejunum and ileum. Met-Enkephalin changed the spontaneous activity of all preparations tested with the exception of the circular preparations ...
R, Radomirov, K, Venkova, M, Davidoff, N, Pencheva   +3 more
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Uptake/internalization of met-enkephalin by brain synaptosomes

Life Sciences, 1983
In this manuscript, we provide evidence for the uptake of met-enkephalin by brain neurons. Tritiated met-enkephalin was accumulated by a crude synaptosomal fraction of rat brain, in the presence of peptidase inhibitors. Characterization of this process in striatum and mediobasal hypothalamus showed incubation time- and temperature-dependence and ...
G R, Van Loon, S R, George
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Plasma met-enkephalin in type I diabetes

Metabolism, 1992
Physiological and pathological evidence suggests that opioid peptides may play a role in glucose homeostasis. We measured plasma levels of beta-endorphin (beta-END) and met-enkephalin (met-ENK) in 22 type I diabetic patients and 15 healthy women (control group).
NEGRI M, TONNARINI, Gian Franco, D'ALESSANDRO, Mariadomenica, FALLUCCA, Francesco   +3 more
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INHIBITION OF THE ENZYMATIC DEGRADATION OF MET-ENKEPHALIN BY CATECHOLAMINES

Endocrinology, 1982
The influence of the catecholamine hormones and some of their metabolites on the enzymatic degradation of met-enkephalin by rat brain homogenates has been evaluated. The enzyme activity was determined by the release of [125I]-tyrosine from radioiodinated met-enkephalin following Porapak Q column chromatography.
J L, Caffrey, D H, Hodges
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In vivo release of met-enkephalin in the cat brain

Neuroscience, 1981
Abstract Push-pull cannulae were implanted into the globus pallidus (anterior part), the caudate nucleus (medio-dorsal part) and the substantia nigra of halothane-anaesthesized cats to study the characteristics of the in vivo release of met-enkephalin. Met-enkephalin was measured by radioimmunoassay (sensitivity: 0.1 pg) and identified by Bio-Gel P
F, Cesselin, P, Soubrié, S, Bourgoin, F, Artaud, T D, Reisine, R, Michelot, J, Glowinski, M, Hamon   +7 more
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Immunomodulation by two potent analogs of met-enkephalin

Immunopharmacology, 1997
Met-enkephalin (Tyr-Gly-Gly-Phe-Met) and its more stable analogs, Tyr-D-Ala-Gly-MePhe-Met-NHC3H gamma-iso (1) and Tyr-D-Ala-Gly-MePhe-Gly-NHC3H gamma-iso (2) significantly enhanced human T-cell proliferation in vitro after 5 days of incubation in the absence of mitogen. The activity was completely inhibited by naloxone, an opioid antagonist.
K, Bajpai, V K, Singh, V C, Dhawan, W, Haq, K B, Mathur, S S, Agarwal   +5 more
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Met-enkephalin effects on associations formed in utero

Peptides, 1982
Rat fetuses exposed to an odor stimulus and an aversive stimulus in utero showed an aversion to the odor when tested 16 days postnatally. Fetuses that also received 80 micrograms/kg Met-enkephalin showed a greater aversion to the odor stimulus than those subjects that did not receive the peptide.
G, Stickrod, D P, Kimble, W P, Smotherman   +2 more
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A characterization of the in vivo immunomodulation by met-enkephalin in mice

International Journal of Immunopharmacology, 1993
Single intraperitoneal injections of Met-enkephalin (MENK) into CBA mice decreased the phagocytic activity of peritoneal macrophages, Con-A-induced proliferation and NK-activity of spleen cells. Conversely, in mice which had been immunized with sheep erythrocytes, treatment with MENK was associated with enhancement of phagocytosis, and no effect on ...
Rabatić, Sabina, Gabrilovac, Jelka, Marotti, Tatjana   +2 more
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Met-enkephalin stimulates secretion of ACTH in sheep

Journal of Endocrinology, 1986
ABSTRACT The ability of opioid peptides to affect plasma immunoreactive ACTH concentrations was examined in conscious sheep. Plasma concentrations of ACTH were significantly increased by an i.v. infusion of Met-enkephalin and its analogue (FK-33824).
X M, Wang, J P, Coghlan, M, Congiu, B A, Scoggins, E M, Wintour   +4 more
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Radioimmunological and immunocytochemical demonstration of met-enkephalin in planaria

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1983
1. An anti-Met-enkephalin serum has been used for radioimmunological and immunocyto-chemical demonstration of Met-enkephalin in planaria. 2. The serum showed a high degree of sensitivity and specificity. 3. Radioimmunoassay demonstrated in planaria extracts a considerable concentration of Met-enkephalin. 4.
VENTURINI G, CAROLEI, ANTONIO, PALLADINI G, MARGOTTA V, LAURO G.   +4 more
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