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CBD Versus CBDP: Comparing In Vitro Receptor-Binding Activities. [PDF]
Int J Mol SciHaghdoost M +5 more
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The assay of Met-enkephalin aminopeptidase with [125I]Met-enkephalin
Journal of Proteomics, 1982Presented here are procedural modifications which permit the utilization of 125I-labeled Met-enkephalin as substrate in the assay of rat brain enkephalin aminopeptidase. Th hydrolysis of enkephalin is monitored by the release of [125I]tyrosine separated on Porapak Q.
James L Caffrey, J L Caffrey
exaly +3 more sources
Peptides, 1984
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
T Yoshimasa +2 more
exaly +3 more sources
Immunohistochemical localization of Met-enkephalin, Met-enkephalin-Arg6-Gly7-Leu8, Met-enkephalin-Arg6-Phe7 and Leu-enkephalin was studied in human adrenal medulla and pheochromocytomas at the light and electron microscopic levels. Both adrenal medulla and pheochromocytomas (4 adrenal, 1 extra-adrenal) showed scattered or clustered cells which ...
T Yoshimasa +2 more
exaly +3 more sources
Peptides, 1992
The effects of Met-enkephalin on the spontaneous and electrically evoked activity were investigated in longitudinal and circular strips isolated from different regions of the large intestine, i.e., proximal colon, distal colon and rectum. Met-enkephalin induced dose-dependent contractile responses which were reversibly blocked by naloxone (10(-6) M ...
K Venkova, R Radomirov
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The effects of Met-enkephalin on the spontaneous and electrically evoked activity were investigated in longitudinal and circular strips isolated from different regions of the large intestine, i.e., proximal colon, distal colon and rectum. Met-enkephalin induced dose-dependent contractile responses which were reversibly blocked by naloxone (10(-6) M ...
K Venkova, R Radomirov
exaly +3 more sources
Dual immunomodulation by met-enkephalin
Brain, Behavior, and Immunity, 1989Met-enkephalin (MENK) is an opioid peptide that is released during physiological stress and is reported to either up-regulate or down-regulate the immune response. Our previous experiments showed the ability of 10(-7) M MENK to modulate the plaque-forming cell (PFC) response of Mishell-Dutton cultures treated with low, optimal, and large concentrations
R R, Rowland, S, Tokuda
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The conversion of met-enkephalin-Arg6, Phe7 to met-enkephalin in rabbit ear artery
Life Sciences, 1983We studied the opioid agonist activities of met-enkephalin-Arg6, Phe7 heptapeptide (ME-A,P) and its D-Ala2-analogue in several isolated organs including rabbit ear artery (ART), guinea-pig ileum (GPI) mouse-, rat and rabbit vas deferens preparation. Both heptapeptides followed the in vitro activity pattern of met-enkephalin (ME).
A Z, Rónai +3 more
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Interaction of met-enkephalin and corticosteroids in immunomodulation
International Journal of Immunopharmacology, 1992The effect of Met-enkephalin (MENK) on several immune functions, corticosterone (CS) and adrenocorticotropin (ACTH) levels in the plasma was studied in adrenalectomized (ADX) and sham-adrenalectomized (SADX) mice. Multiple Met-enkephalin injections (10 mg/kg per day in two injections 12 h apart, for 4 days) increased the plaque-forming cell response to
Gabrilovac, Jelka +3 more
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Life Sciences, 1983
Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
M, Sakamoto +6 more
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Studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin A from adrenal medulla and human pheochromocytoma have revealed that this precursor contains 4 copies of methionine-enkephalin(Met-Enk) and one copy each of leu-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8(Met-Enk-Arg6-Gly7-Leu8) and methionine ...
M, Sakamoto +6 more
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