Results 71 to 80 of about 50,179,594 (344)

CSF and blood levels of Neurofilaments, T-Tau, P-Tau, and Abeta-42 in amyotrophic lateral sclerosis: a systematic review and meta-analysis

Journal of Translational Medicine
Recent literature suggests that markers of neuroaxonal damage, such as neurofilaments and tau protein, might serve as potential biomarkers for ALS. We conducted this systematic review and meta-analysis study to compare cerebrospinal fluid (CSF) and blood
Elmira Agah, Helia Mojtabavi, Atefeh Behkar, Arash Heidari, Atra Ajdari, Zoha Shaka, Seyed Vahid Mousavi, Negar Firoozeh, Abbas Tafakhori, Nima Rezaei   +9 more
doaj   +1 more source

Biologics and oral systemic treatment preferences in patients and physicians for moderate-to-severe atopic dermatitis: a discrete choice experiment in the United Kingdom and Germany

Journal of Dermatological Treatment
Background: As the available treatments for moderate-to-severe atopic dermatitis (AD) expand, understanding patient and physician preferences becomes crucial for informed decision-making.Objective: To quantify patient and physician preferences for ...
Nicholas Durno, Pablo Arija, Krystallia Pantiri, Marieke Heisen, Marco Boeri, Josef Paris, Katrin Jack, Olivier Chambenoit, Ramkumar Subramanian, Jorge Puelles, Elly Stolk, Ben van Hout, Jonathan I. Silverberg   +12 more
doaj   +1 more source

Propensity Score-Based Approaches to Confounding by Indication in Individual Patient Data Meta-Analysis: Non-Standardized Treatment for Multidrug Resistant Tuberculosis. [PDF]

PLoS ONE, 2016
BACKGROUND:In the absence of randomized clinical trials, meta-analysis of individual patient data (IPD) from observational studies may provide the most accurate effect estimates for an intervention. However, confounding by indication remains an important
Gregory J Fox, Andrea Benedetti, Carole D Mitnick, Madhukar Pai, Dick Menzies, Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB   +5 more
doaj   +1 more source

Practical methods for incorporating summary time-to-event data into meta-analysis

Trials, 2007
BackgroundIn systematic reviews and meta-analyses, time-to-event outcomes are most appropriately analysed using hazard ratios (HRs). In the absence of individual patient data (IPD), methods are available to obtain HRs and/or associated statistics by ...
J. Tierney, L. Stewart, D. Ghersi, S. Burdett, M. Sydes   +4 more
semanticscholar   +1 more source

rgs212/Meta-analysis-Smith: Methylation Meta analysis Smith et al

, 2021
Release of "A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex" by Smith and Pishva et al ...
Gemma Shireby, Gilles Gasparoni, Ehsan Pishva, Rebecca G. Smith, Gregory Wheildon, Vahram Haroutunian, Daniel L.A. van den Hove, Andrew J. Sharp, Janou A.Y. Roubroeks, Armin Giese, Wolfgang Viechtbauer, Katie Lunnon, Adam R. Smith, Paul D. Coleman, Eilis Hannon, Diego Mastroeni, Jonathan Mill, Michael Weedon, Jörn Walter, David A. Bennett, Leonard Schalkwyk, Matthias Riemenschneider, Philip L. De Jager   +22 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

METAL: fast and efficient meta-analysis of genomewide association scans

Bioinform., 2010
Summary: METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies.
C. Willer, Yun Li, G. Abecasis
semanticscholar   +1 more source

Meta-analysis in Otolaryngology [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2000
To examine the results of meta-analyses in otolaryngology and compare these results with the individual component studies that constitute each meta-analysis.A retrospective review of the literature.Studies that conducted pooled statistical systematic analyses indexed on MEDLINE for the 10-year period from January 1989 to January 1999 were selected for ...
R, Alsarraf, N W, Alsarraf, B M, Kato, N D, Goldman   +3 more
openaire   +2 more sources

Informe de práctica empresarial, Alcaldía de Restrepo

, 2023
Informe de práctica profesional del programa de Comunicación Social y PeriodismoLa Alcaldía de Restrepo se crea cuando por medio del Decreto 904 del 23 de septiembre de 1912 cuando el caserío La Concepción fue elevado a la categoría de municipio ...
Sandoval Cisneros, Laura Camila
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source