Results 61 to 70 of about 246,640 (339)

Short-term efficacy and safety of low-intensity extracorporeal shock wave therapy in erectile dysfunction: a systematic review and meta-analysis

open access: yesInternational Brazilian Journal of Urology
Aim: The role of low-intensity extracorporeal shock wave therapy (LI-ESWT) in erectile dysfunction (ED) is not clearly determined. The purpose of this study is to investigate the short-term efficacy and safety of LI-ESWT for ED patients.
Zi-jun Zou   +8 more
doaj   +1 more source

Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea. Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.
Milton Rodriguez-Zuniga   +2 more
doaj   +1 more source

A warning to readers about the term metanalysis in non-systematic reviews about diabetic retinopathy: documental study

open access: yesJournal of Evidence-Based Healthcare, 2021
BACKGROUND: Meta-analysis is a very seductive term in scientific papers because it summarizes a compilation of quantitative results; however its interpretation must be done carefully.
Vania Mozetic   +5 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Topical Agents in Biofilm Disaggregation: A Systematic Review and Meta-Analysis

open access: yesJournal of Clinical Medicine
Background: to evaluate the effectiveness of different topical agents in biofilm disaggregation during non-surgical periodontal therapy. Methods: the search strategy was conducted according to the PRISMA 2020 on Pubmed, Cochrane Library, Scopus, and Web of Science, and it was registered in PROSPERO, ID: CRD42023474232. It included studies comparing non-
Pardo, Alessia   +6 more
openaire   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Tamsulosin vs. Tadalafil as medical expulsive therapy for distal ureteral stones: a systematic review and meta-analysis [PDF]

open access: yesInternational Brazilian Journal of Urology
Purpose: Medical expulsive therapy (MET) is recommended for distal ureteral stones from 5 to 10 mm. The best drug for MET is still uncertain. In this review, we aim to compare the effectiveness of tadalafil and tamsulosin for distal ureteral stones from ...
Mikhael Belkovsky   +5 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Male and Female Physician Suicidality: A Systematic Review and Meta-analysis.

open access: yesJAMA psychiatry, 2020
Importance Population-based findings on physician suicide are of great relevance because this is an important and understudied topic. Objective To evaluate male and female physician suicide risks compared with the general population from 1980 to date ...
D. Duarte   +5 more
semanticscholar   +1 more source

Concepts and emerging issues of network meta-analysis

open access: yesKorean Journal of Anesthesiology, 2021
Most diseases have more than two interventions or treatment methods, and the application of network meta-analysis (NMA) studies to compare and evaluate the superiority of each intervention or treatment method is increasing. Understanding the concepts and
E. Ahn, Hyun Kang
semanticscholar   +1 more source

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