Results 61 to 70 of about 931,154 (348)

Neutrophil extracellular traps predict poor survival in cancer: a systematic review and meta-analysis of studies on tissue and circulating biomarkers

open access: yesFrontiers in Immunology
BackgroundNeutrophil extracellular traps (NETs) are fibrous, web like chromatin structures released by activated neutrophils that entrap and immobilize pathogens through histones, granule derived proteolytic enzymes, and myeloperoxidase (MPO) dependent ...
Seungwoo Lee   +4 more
doaj   +1 more source

Reslizumab versus placebo for poorly controlled, severe eosinophilic asthma: Meta-analysis [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. Reslizumab is humanized monoclonal antibody produced by recombinant DNA technology which binds to circulating interleukin-5 (IL-5) and down-regulates the IL-5 signaling pathway. Reslizumab is indicated for the add-on maintenance treatment
Milosavljević Miloš N.   +5 more
doaj   +1 more source

Binding Potassium to Improve Treatment With Renin-Angiotensin-Aldosterone System Inhibitors: Results From Multiple One-Stage Pairwise and Network Meta-Analyses of Clinical Trials

open access: yesFrontiers in Medicine, 2021
This manuscript presents findings from the first dichotomous data pooling analysis on clinical trials (CT) regarding the effectiveness of binding potassium.
Frank Lizaraso-Soto   +20 more
doaj   +1 more source

Towards evaluation of personalized and collaborative information retrieval [PDF]

open access: yes, 2011
We propose to extend standard information retrieval (IR) ad-hoc test collection design to facilitate research on personalized and collaborative IR by gathering additional meta-information during the topic (query) development process.
Ganguly, Debasis   +3 more
core   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

An alternative approach to deal with the absence of clinical trials: a proportional meta-analysis of case series studies [PDF]

open access: yesActa Cirúrgica Brasileira, 2013
PURPOSE: Systematic reviews are criticized for frequently offering inconsistent evidences and absence of straightforward recommendations. Their value seems to be depreciated when the conclusions are uncertain.
Regina El Dib   +2 more
doaj   +2 more sources

Corporate governance in banks: systematic literature review and meta-analysis [PDF]

open access: yes, 2018
This paper provides a two steps investigation of the literature on banking corporate governance. We firstly perform a systematic literature review on the academics papers focused on risk management, compensation and ownership structure of banks.
Lagasio, Valentina
core   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Revisão sistemática da acurácia dos testes diagnósticos: uma revisão narrativa

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Este artigo tem o objetivo de realizar uma revisão narrativa sobre revisão sistemática da acurácia dos testes diagnósticos. Foi realizada busca na Cochrane Methodology Reviews (Cochrane Reviews of Diagnostic Test Accuracy), Medline e LILACS, bem como ...
Glória Maria de Oliveira   +4 more
doaj   +1 more source

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