Results 151 to 160 of about 85,333 (258)

Toll of Chronic Metabolic Acidosis at Molecular, Cellular, and Systemic Levels: A Conceptual Framework to Revisit Type 2 Diabetes (T2D) Pathophysiology. [PDF]

Biomedicines
Sater MS, Giha HA.
europepmc   +1 more source

Anaesthetic management of a horse with acute kidney injury

Equine Veterinary Education, EarlyView.
Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley   +1 more source

Sodium bicarbonate application for the treatment of acute metabolic acidosis: what we know and what we still don't know. [PDF]

Intensive Care Med
von Groote T, Langer T, Brunoni B.
europepmc   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Sodium bicarbonate therapy for metabolic acidosis in children stratified by acute kidney injury status and chloride levels: a retrospective cohort study. [PDF]

Transl Pediatr
Meng X, Qiu C, Huang H, Hong Y, Xiao R, Han M, Bai Z, Xu Y, Liu H, Wu S.   +9 more
europepmc   +1 more source

A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination

The FEBS Journal, EarlyView.
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam, Tadtarit Anujareewat, Wachirawit Chinantuya, Pratchaya Watthaisong, Chayasith Uttamapinant, Somchart Maenpuen, Ruchanok Tinikul   +6 more
wiley   +1 more source

Evolutive acid-base derangements in critically ill patients: epidemiological aspects, association with mortality and metabolic acidosis prediction. [PDF]

Crit Care Sci
Faria CC, Paiva CLN, Araujo LMA, Cardozo Júnior LCM, Park M.   +4 more
europepmc   +1 more source

Waist‐to‐height ratio and renal dysfunction as independent correlates of low handgrip strength in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
In 1,468 patients with type 2 diabetes, central obesity (WHtR >0.5) neutralizes the protective effects of higher BMI on muscle strength. Concurrently, visceral adiposity and CKD impose an additive threat, maximizing low handgrip strength risk (aOR = 1.74). Combining WHtR and renal tracking optimizes clinical sarcopenia screening.
Shing‐Hua Chen, Chen‐Kai Chou, Shao‐Wen Weng, Jung‐Fu Chen, Feng‐Chih Shen   +4 more
wiley   +1 more source

Veverimer in treating metabolic acidosis in chronic kidney disease patients: a systematic review and meta-analysis of randomized clinical trials. [PDF]

BMC Nephrol
Islampanah M, Karami S, Salehi S, Akbari A, Noradini A, Tafazolimoghadam A, Yousefi S, Pirzad S.   +7 more
europepmc   +1 more source