Acidic pH triggers GOT1 phase separation via IDR1, recruiting ME1 to form ROS‐scavenging condensates that combat senescence, revealed by a FLIM‐based pH probe. Abstract Cellular senescence involves progressive acidification, but how cells sense and adapt to this pH shift remains unclear.
Ziyue Chen +8 more
wiley +1 more source
Transcending metabolic acidosis: lactate as an epigenetic signal reprogramming diabetes-sepsis immunity. [PDF]
Cai X, Han L, Liang Q.
europepmc +1 more source
Abstract Introduction Metabolic acidosis is common in dogs with chronic kidney disease (CKD) and induces ventilatory compensation. Systemic arterial hypertension frequently accompanies CKD, but its influence on the ventilatory response remains unclear.
Letícia da Silva Rueda +7 more
wiley +1 more source
Case Report: A Previously Healthy Young Woman With Lethal, Unremitting Metabolic Acidosis: Could a Novel Variant in <i>ALAS2</i> Be the Culprit? [PDF]
Brown G, Brown S.
europepmc +1 more source
This guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) outlines best practices for managing abdominal blast injuries in resource‐limited environments, especially after blast injuries from explosive ordnance including improvised explosive devices.
Sara Barbara Anna Morel +9 more
wiley +1 more source
Multiple Carboxylase Deficiency in an Infant Presenting With Severe Metabolic Acidosis and Sepsis-Like Features: A Case Report and Literature Review. [PDF]
Rehman T +8 more
europepmc +1 more source
Adjusting Our Thinking About Feeding Animals: Fiber as the Metric for Mimicking Natural Diets
A typical effect of the change of an animal group to a diet higher in fiber: juveniles keep growing, animals of ideal body weight maintain their weight, and obese individuals lose weight. ABSTRACT Free‐ranging animals often ingest markedly different diets than their counterparts under human care, whether companion animals, production animals, or zoo ...
Marcus Clauss +4 more
wiley +1 more source
Preoperative hyperchloraemia and intraoperative metabolic acidosis in infants undergoing anorectal pull-through for Hirschsprung's disease: A retrospective observational study. [PDF]
Chan EEH, Shenoy U, Challa SKR, Rai R.
europepmc +1 more source
Feeding Practices and Welfare of Zoo‐Housed Giraffes (Giraffa camelopardalis) on a Global Scale
We collected feeding and stereotypy information on 702 giraffes from 146 zoos from all over the world. Less appropriate diets were linked to more oral stereotypies. ABSTRACT Since giraffe feeding practices have only been reported for European and US facilities, this study aimed to achieve a comprehensive overview of the current giraffe feeding ...
Rosalyn Pardave +3 more
wiley +1 more source
Association between food group intakes and metabolic acidosis in patients with non-dialysis-dependent chronic kidney disease. [PDF]
Morimoto N +13 more
europepmc +1 more source

