Results 191 to 200 of about 85,333 (258)

Brain strain: Blood flow and metabolism in environmental extremes

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak   +3 more
wiley   +1 more source

The acute effects of exercise intensity and inorganic nitrate supplementation on the Buckberg ratio in postmenopausal females

open access: yesExperimental Physiology, EarlyView.
Abstract Menopause increases coronary heart disease risk, in part through reduced oestrogen‐mediated nitric oxide (NO) bioavailability. The Buckberg ratio, an index of myocardial oxygen supply–demand balance, in which higher values reflect more favourable myocardial perfusion, is lower in postmenopausal females (PMFs) than in age‐matched males.
Cassandra C. Derella   +6 more
wiley   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich   +5 more
wiley   +1 more source

The ratio of chloride to bicarbonate is a predictor of advanced metabolic acidosis in CKD stages G4 and G5. [PDF]

open access: yesSci Rep
Korus J   +10 more
europepmc   +1 more source

Sodium bicarbonate administration for metabolic acidosis in the intensive care unit: a target trial emulation. [PDF]

open access: yesIntensive Care Med
Blank SP   +14 more
europepmc   +1 more source

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