Results 161 to 170 of about 1,243,890 (293)

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Levetiracetam-associated high-anion gap metabolic acidosis and secondary ketogenesis: a case series. [PDF]

Clin Kidney J
Al-Baqain K, Sharawi S, Khabbaz O, Ghishan S, Ash-Shawareb Y, Kheetan M, Shweihat Y, Khitan Z.   +7 more
europepmc   +1 more source

Metabolic acidosis.

Acta medica Indonesiana, 2007
Acute metabolic acidosis is frequently encountered in critically ill patients. Metabolic acidosis can occur as a result of either the accumulation of endogenous acids that consumes bicarbonate (high anion gap metabolic acidosis) or loss of bicarbonate from the gastrointestinal tract or the kidney (hyperchloremic or normal anion gap metabolic acidosis).
openaire   +1 more source

Targeting the Subthalamic Nucleus in MEGDEL Syndrome: A Case Report of a Clinically Effective Intervention for Debilitating Lingual Dyskinesia and Dystonia

Movement Disorders Clinical Practice, EarlyView.
Philipp Köberle, Florian Lange, Ghadir Abbas, Philipp Capetian, Marius Vogt, Patrick Fricke, Cordula Matthies, Jens Volkmann, Martin Reich, Thomas Musacchio   +9 more
wiley   +1 more source

Fenestrated Microneedle Biosensor for Continuous In Vivo Lactate Monitoring in Interstitial Fluid

Small, EarlyView.
A fenestrated microneedle biosensor enables continuous transdermal monitoring of lactate in interstitial fluid while protecting the functional sensing interface during insertion into the skin. The platform delivers sensitive electrochemical lactate detection and distinguishes metabolic profiles in healthy and type 2 diabetic‐obese mice, and captures ...
Masoud Khazaei, Ali‐Reza Shokouhi, Parham Sahandi Zangabad, Victor J. Cadarso, Muamer Dervisevic, Nicolas H. Voelcker   +5 more
wiley   +1 more source

Bicarbonate and Other Buffer Therapies in Acute Metabolic Acidosis: A Systematic Review and Meta-Analysis. [PDF]

Acta Anaesthesiol Scand
Lind PC, Hansen FG, Holmberg MJ, Jessen MK, Granfeldt A, Andersen LW.   +5 more
europepmc   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source

Intentional Naproxen Overdose Causing Metabolic Acidosis: A Case Report. [PDF]

Cureus
Falatovich B, Isom B.
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Pendrin inhibitor PDSinh-C01 reverses salt-sensitive hypertension and metabolic acidosis in the 5/6 nephrectomy rat model. [PDF]

Pflugers Arch
Rudolphi CF, Goos Y, Musterd-Bhaggoe U, van Veghel R, Garrelds IM, Danser AHJ, Karmakar J, Cil O, Imenez Silva PH, Hoorn EJ.   +9 more
europepmc   +1 more source