Results 41 to 50 of about 345,589 (262)

Development of a Lot-Sizing Model to Prevent Heat Stress and Work-Related Musculoskeletal Disorders

Promet (Zagreb), 2021
Management of heat stress and metabolic cost is vital for preventing any work-related disorders. In this paper, we integrated rest time formulations for heat strain and metabolic cost to develop a new lot sizing model for preventing heat exposure and ...
Sezen Korkulu, Krisztián Bóna
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Efficiency analysis of different approaches to the third stage of long-term training in team games [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
Efficiency of construction of the third stage of long-term preparation of young sportsmen is certain. In researches 187 players took part in age 16-18 years.
Maksimenko I.G.
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Improving Muscle Force Distribution Model Using Reflex Excitation: Toward a Model-Based Exoskeleton Torque Optimization Approach

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
In this study, we improve the existing model for force distribution over the muscles by considering reflex excitation as a nonvoluntary mechanism of our neuromuscular system.
Mojtaba Rayati, Rezvan Nasiri, Majid Nili Ahmadabadi   +2 more
doaj   +1 more source

The metabolic costs of meiotic drive

Proceedings of the Royal Society B: Biological Sciences
Abstract Selfish genetic elements, such as meiotic drive genes, disrupt Mendel’s law of equal segregation by biasing their own transmission, often at a detriment to the rest of the genome. The Malaysian stalk-eyed fly ( Teleopsis dalmanni) sex-ratio (SR) meiotic drive system is ...
Sasha L Bradshaw, Enrique Rodriguez, Hanting Wang, Cyn Thea Yu, Cyril De Villiers De La Noue, Aadil Hafezjee, Andrew Pomiankowski, M. Florencia Camus   +7 more
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Biomechanical and Physiological Evaluation of a Multi-Joint Exoskeleton with Active-Passive Assistance for Walking

Biosensors, 2021
How to improve the walking efficiency while ensuring the wearability is an important issue of lower limb exoskeletons. Active devices can provide greater forces, while the passive devices have advantage in weight.
Wujing Cao, Zhewen Zhang, Chunjie Chen, Yong He, Dashuai Wang, Xinyu Wu   +5 more
doaj   +1 more source

Metabolic costs of hybridization in Newts

Folia Zoologica, 2012
Abstract. Heterospecific hybrids often suffer from a lowered fitness relative to parental species. Contextdependent intrinsic costs of hybridization are partially due to a malfunction in cell biochemical machinery that affects metabolic rates at the organismal level.
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source