Results 51 to 60 of about 345,589 (262)

How Plant Toxins Cause Early Larval Mortality in Herbivorous Insects: An Explanation by Modeling the Net Energy Curve

Toxins
Plants store chemical defenses that act as toxins against herbivores, such as toxic isothiocyanates (ITCs) in Brassica plants, hydrolyzed from glucosinolate (GLS) precursors.
Suman Chakraborty, Stefan Schuster
doaj   +1 more source

Mapping the Energetic Costs of Free-Swimming Gilthead Sea Bream (Sparus aurata), a Key Species in European Marine Aquaculture

Biology, 2021
Measurement of metabolic rates provides a valuable proxy for the energetic costs of different living activities. However, such measurements are not easy to perform in free-swimming fish. Therefore, mapping acceleration from accelerometer tags with oxygen
Sébastien Alfonso, Walter Zupa, Maria Teresa Spedicato, Giuseppe Lembo, Pierluigi Carbonara   +4 more
doaj   +1 more source

METABOLIC COST AS AN ORGANIZING PRINCIPLE FOR COOPERATIVE LEARNING [PDF]

Advances in Complex Systems, 2013
This article investigates how neurons can use metabolic cost to facilitate learning at a population level. Although decision-making by individual neurons has been extensively studied, questions regarding how neurons should behave to cooperate effectively remain largely unaddressed.
David Balduzzi, Pedro A. Ortega, Michel Besserve   +2 more
openaire   +6 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Modeling and Prediction of Wearable Energy Harvesting Sliding Shoes for Metabolic Cost and Energy Rate Outside of the Lab

Sensors, 2020
The recent explosion of wearable electronics has led to widespread interest in harvesting human movement energy, particularly during walking, for clinical and health applications.
Peter B. Shull, Haisheng Xia
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Dogs Have the Most Neurons, Though Not the Largest Brain: Trade-Off between Body Mass and Number of Neurons in the Cerebral Cortex of Large Carnivoran Species

Frontiers in Neuroanatomy, 2017
Carnivorans are a diverse group of mammals that includes carnivorous, omnivorous and herbivorous, domesticated and wild species, with a large range of brain sizes.
Débora Jardim-Messeder, Kelly Lambert, Stephen Noctor, Fernanda M. Pestana, Maria E. de Castro Leal, Mads F. Bertelsen, Abdulaziz N. Alagaili, Osama B. Mohammad, Paul R. Manger, Suzana Herculano-Houzel, Suzana Herculano-Houzel, Suzana Herculano-Houzel   +11 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Evaluating acute stress responses to height: validity of heart rate variability, respiratory markers, and competitive state anxiety inventory

Frontiers in Psychology
Despite the widespread use of height exposure in adventure-based programs to foster resilience, effectiveness has largely been evaluated through self-reported measures, with limited objective psychophysiological assessments.
Lukáš Psohlavec, Mike Rogerson, Tomáš Brtník, Jiří Baláš   +3 more
doaj   +1 more source