Results 1 to 10 of about 1,855,857 (359)

Rare diseases leading to childhood Glaucoma. epidemiology, pathophysiogenesis, and management [PDF]

, 2015
Noteworthy heterogeneity exists in the rare diseases associated with childhood glaucoma. Primary congenital glaucoma is mostly sporadic; however, 10% to 40% of cases are familial. CYP1B1 gene mutations seem to account for 87% of familial cases and 27% of
Abdolrahimzadeh, Solmaz, CONTESTABILE, Maria Teresa, FAMELI, VALERIA, Mollo, Roberto, Perdicchi, Andrea, RECUPERO, Santi Maria   +5 more
core   +11 more sources

Evidence and Potential Mechanisms of Traditional Chinese Medicine for the Adjuvant Treatment of Coronary Heart Disease in Patients with Diabetes Mellitus: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

Journal of Diabetes Research, 2022
Traditional Chinese medicine (TCM) has long been used to treat diabetes mellitus and angina. It has also gained widespread clinical applications in China as a common adjuvant treatment.
Yu Wei, Qi-You Ding, Chak Yeung, Yi-shan Huang, Bo-xun Zhang, Li-li Zhang, Run-Yu Miao, Sha Di, Lin-Hua Zhao, Xiao-Lin Tong   +9 more
doaj   +1 more source

Clinical Characteristics of Target Organ Damage in Primary Aldosteronism with or without Metabolic Syndrome

Journal of Diabetes Research, 2022
The aim of this study is to investigate the prevalence of metabolic disorders in patients with primary aldosteronism (PA) and target organ damage (TOD) in different subtypes of patients with PA with or without metabolic syndrome (MS).
Xiaona Bu, Fang Sun, Hexuan Zhang, Xiaoli Liu, Zhigang Zhao, Hongbo He, Yingsha Li, Zhencheng Yan, Zhiming Zhu   +8 more
doaj   +1 more source

Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump

International Journal of Endocrinology, 2022
Background. Lipohypertrophy (LH) of subcutaneous tissue is an insulin-induced complication occurring in patients with diabetes. We aimed to define the prevalence of LH and identify its risk factors in type 1 diabetes (T1DM) patients treated with ...
Damian Ucieklak, Sandra Mrozinska, Aleksandra Wojnarska, Maciej T. Malecki, Tomasz Klupa, Bartłomiej Matejko   +5 more
doaj   +1 more source

Glucocorticoids, metabolism and metabolic diseases [PDF]

Molecular and Cellular Endocrinology, 2007
Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Vegiopoulos, Alexandros, Herzig, Stephan
openaire   +3 more sources

Differential Expression and Bioinformatics Analysis of Plasma-Derived Exosomal circRNA in Type 1 Diabetes Mellitus

Journal of Immunology Research, 2022
Backgrounds. Both exosome and circular RNA (circRNA) have been reported to participate in the pathogenesis of type 1 diabetes mellitus (T1DM). However, the exact role of exosomal circRNA in T1DM is largely unknown.
Haipeng Pang, Wenqi Fan, Xiajie Shi, Shuoming Luo, Yimeng Wang, Jian Lin, Yang Xiao, Xia Li, Gan Huang, Zhiguo Xie, Zhiguang Zhou   +10 more
doaj   +1 more source

Fructose metabolism and metabolic disease [PDF]

Journal of Clinical Investigation, 2018
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful.
Herman, Mark A, Hannou, Sarah A, McKeown, Nicola M, Haslam, Danielle E   +3 more
openaire   +2 more sources

Interaction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine

Gut Pathogens, 2021
Background The liver plays an important role in production and metabolism of homocysteine (Hcy), which has been reported to be involved in liver injury. In our previous work, we confirm that Hcy can induce liver injury by activating endoplasmic reticulum
Kun Xiao, Shengchao Ma, Long Xu, Ning Ding, Hui Zhang, Lin Xie, Lingbo Xu, Yun Jiao, Huiping Zhang, Yideng Jiang   +9 more
doaj   +1 more source

Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals

Nutrition & Metabolism, 2021
Context Body composition may explain partially why non-obese individuals still at the risk of developing non-alcoholic fatty liver disease (NAFLD).
Huajie Dai, Jiali Xiang, Yanan Hou, Liping Xuan, Tiange Wang, Mian Li, Zhiyun Zhao, Yu Xu, Jieli Lu, Yuhong Chen, Weiqing Wang, Guang Ning, Yufang Bi, Min Xu   +13 more
doaj   +1 more source

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]

, 2020
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R, Banerjee, R, Bell, J.D., Bell, J.D., Hemingway, H., Hemingway, H., Hingorani, A.D., Hingorani, A.D., Kelly, M., Kelly, M., McGonigle, J., McGonigle, J., Neubauer, S., Neubauer, S., Nicholls, R.C., Nicholls, R.C., Parisinos, C.A., Parisinos, C.A., Patel, R.S., Patel, R.S., Thomas, E.L., Thomas, E.L., Wilman, H., Wilman, H., Yaghootkar, H., Yaghootkar, H.   +25 more
core   +3 more sources