Results 11 to 20 of about 996,145 (295)
Cellular metabolism and diseases [PDF]
British Journal of Pharmacology, 2021 LINKED ARTICLESThis article is part of a themed issue on Cellular metabolism and diseases. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v178.10 ...
Pasquale Maffia +3 more
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Glucocorticoids, metabolism and metabolic diseases [PDF]
Molecular and Cellular Endocrinology, 2007 Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Stephan Herzig, Alexandros Vegiopoulos
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Retinal Disease and Metabolism [PDF]
Life, 2022 Retinal diseases, such as diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinopathy of prematurity (ROP), are some of the leading causes of blindness all over the world [...]
Zhongjie Fu +3 more
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Fructose metabolism and metabolic disease [PDF]
Journal of Clinical Investigation, 2018 Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful.
Herman, Mark A +3 more
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MicroRNAs in Metabolism and Metabolic Diseases [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2011 Aberrant cholesterol/lipid homeostasis is linked to a number of diseases prevalent in the developed world, including metabolic syndrome, type II diabetes, and cardiovascular disease. We have previously uncovered gene regulatory mechanisms of the sterol regulatory element-binding protein (SREBP) family of transcription factors, which control the ...
S H Najafi-Shoushtari +10 more
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Nutrition & Metabolism, 2021 Background We aimed to define refined body shapes by using multiple anthropometric traits that represent fat distribution, and evaluate their associations with risk of insulin resistance (IR) and cardiometabolic disorders in a Chinese population. Methods
Yulin Zhou +14 more
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Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study [PDF]
Journal of Stroke, 2023 Background and Purpose We investigated the causal relationships between the gut microbiota (GM), stroke, and potential metabolite mediators using Mendelian randomization (MR).
Qi Wang +17 more
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Cardiovascular Diabetology, 2023 Background Gut microbiota imbalances have been suggested as a contributing factor to atrial fibrillation (AF), but the causal relationship is not fully understood.
Huajie Dai +18 more
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Nutrition & Metabolism, 2023 Background Metabolic dysfunction is a major determinant in the progression of fatty liver disease. It is pivotal to evaluate the metabolic status and subsequent transition in fatty liver population and to identify the risk of subclinical atherosclerosis.
Zhuojun Xin +15 more
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Cancer as a metabolic disease [PDF]
Nutrition & Metabolism, 2010 Emerging evidence indicates that impaired cellular energy metabolism is the defining characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal cells, which derive most of their usable energy from oxidative phosphorylation, most cancer cells become heavily dependent on substrate level phosphorylation to meet ...
Thomas N. Seyfried, Laura M. Shelton
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