Results 241 to 250 of about 1,855,857 (359)

Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease

, 2020
O. Yu. Kytikovа, Т. П. Новгородцева, Yulia Denisenko, D. A. Kovalevsky   +3 more
openalex   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The Evolving Trend of Liver Transplantation in Metabolic Diseases: From Origins to Current Perspectives. [PDF]

J Inherit Metab Dis
Pietrobattista A, Martinelli D, Spada M, Dionisi-Vici C.   +3 more
europepmc   +1 more source

Central mechanisms of obesity and related metabolic diseases. [PDF]

Rev Endocr Metab Disord, 2013
Cai D.
europepmc   +1 more source

Metabolic Syndrome Causes Cardiovascular Disease under Stable Statin Medication

, 2017
Sang‐Cheol Cho, Hoonhee Lee, Hyo-Jung Nam, Ki Hoon Han   +3 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Editorial: The impact of GIP/GIPR on metabolic diseases: how the field is evolving. [PDF]

Front Endocrinol (Lausanne)
Habegger K, Tomas A, Chen R, Harris C, Roell W, Coskun T.   +5 more
europepmc   +1 more source

PREVALENCE OF METABOLIC SYNDROME IN CORONARY ARTERY DISEASE AND CEREBROVASCULAR ACCIDENT PATIENTS

, 2019
G. Ramakrishna, Kalyan Kumar P V, Rohan Ramakrishna   +2 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Microbiota-Mediated Bile Acid Metabolism as a Mechanistic Framework for Precision Nutrition in Gastrointestinal and Metabolic Diseases. [PDF]

Cells
Kang S, Jeong DY, Seo J, Daily JW, Park S.   +4 more
europepmc   +1 more source