Results 21 to 30 of about 996,145 (295)
Cardiovascular Diabetology, 2021 Background The triglyceride-glucose index (TyG index) has been proposed as a simple and reliable alternative insulin resistance (IR) marker, while the homeostasis model assessment for IR (HOMA-IR) is the most frequently used index.
Shujie Wang +8 more
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Polyphenols in Metabolic Diseases
Molecules, 2022 Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. Considering their free-radical scavenging and anti-inflammatory properties,
Amin Gasmi +13 more
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CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity
Cell Death and Disease, 2021 Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT)
Linlin Zhang +12 more
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Roczniki Panstwowego Zakladu Higieny, 2019 Background. It has been established that in Type 1 Diabetes Mellitus (T1DM), regardless of the insulin therapy model used, diet and proper eating habits are still important in the treatment of the disease.
Sabina Krzyżowska +5 more
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Cardiovascular Diabetology, 2023 Background Glycemic variability plays an important role in the development of cardiovascular disease (CVD). This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic stiffness progression in participants
Qianhua Fang +11 more
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Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome
Nature Communications, 2021 Male sex is a risk factor for impaired glucose metabolism and type 2 diabetes. Here the authors identify that androgen modulates the gut microbiome, which drives insulin resistance and contributes to sexual dimorphism in glucose metabolism in mice.
Aibo Gao +20 more
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Scientific Reports, 2017 Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of
Arwen W. Gao +13 more
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Association between Serum Magnesium and Hemoglobin in Patients with Primary Hyperparathyroidism
International Journal of Endocrinology, 2021 Background. There is a positive association between serum magnesium and hemoglobin levels in the general population. However, no studies have evaluated the association between serum magnesium and hemoglobin levels in patients with primary ...
Na Ding +8 more
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Journal of Translational Medicine, 2023 Background Observational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between omega-3 fatty acids and type 2 diabetes. We aim to evaluate the causal effect of omega-3 fatty acids on
Chunyan Hu +21 more
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Cell Death Discovery, 2022 BMP9 inhibits cellular senescence by activation of Smad1, which suppresses the transcription of Stat1, resulting in decreased P21 expression and SASPs production in osteoblast.
Jing-zun Xu +11 more
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