Results 21 to 30 of about 1,855,857 (359)

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Risk of subclinical atherosclerosis across metabolic transition in individuals with or without fatty liver disease: a prospective cohort study

Nutrition & Metabolism, 2023
Background Metabolic dysfunction is a major determinant in the progression of fatty liver disease. It is pivotal to evaluate the metabolic status and subsequent transition in fatty liver population and to identify the risk of subclinical atherosclerosis.
Zhuojun Xin, Jiaojiao Huang, Qiuyu Cao, Jialu Wang, Ruixin He, Tianzhichao Hou, Yi Ding, Jieli Lu, Tiange Wang, Zhiyun Zhao, Weiqing Wang, Guang Ning, Min Xu, Yufang Bi, Yu Xu, Mian Li   +15 more
doaj   +1 more source

Peri-implant diseases and metabolic syndrome components: a systematic review [PDF]

, 2018
OBJECTIVE: Metabolic syndrome (MetS) is defined as a spectrum of conditions associated with an increased risk of developing CVD and type 2 diabetes.
Letizia, C, Papi, P, Petramala, L, Pilloni, A, Pompa, G, Rosella, D, Saraceno, V   +6 more
core   +1 more source

Assessment of selected food intake frequency in patients with type 1 diabetes treated with personal insulin pumps

Roczniki Panstwowego Zakladu Higieny, 2019
Background. It has been established that in Type 1 Diabetes Mellitus (T1DM), regardless of the insulin therapy model used, diet and proper eating habits are still important in the treatment of the disease.
Sabina Krzyżowska, Bartłomiej Matejko, Beata Kieć-Wilk, Magdalena Wilk, Maciej Małecki, Tomasz Klupa   +5 more
doaj   +1 more source

CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity

Cell Death and Disease, 2021
Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT)
Linlin Zhang, Chunxiang Sheng, Feiye Zhou, Kecheng Zhu, Shushu Wang, Qianqian Liu, Miaomiao Yuan, Zhaoqian Xu, Yun Liu, Jieli Lu, Jianmin Liu, Libin Zhou, Xiao Wang   +12 more
doaj   +1 more source

Physiological conditions influencing regenerative potential of stem cells [PDF]

, 2016
Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele, De Falco, Elena, Gambini, Elisa, Spaltro, Gabriella   +3 more
core   +1 more source

A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

Scientific Reports, 2017
Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of
Arwen W. Gao, Iliana A. Chatzispyrou, Rashmi Kamble, Yasmine J. Liu, Katharina Herzog, Reuben L. Smith, Henk van Lenthe, Martin A. T. Vervaart, Arno van Cruchten, Angela C. Luyf, Antoine van Kampen, Mia L. Pras-Raves, Frédéric M. Vaz, Riekelt H. Houtkooper   +13 more
doaj   +1 more source

Evaluating the distinct pleiotropic effects of omega-3 fatty acids on type 2 diabetes mellitus: a mendelian randomization study

Journal of Translational Medicine, 2023
Background Observational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between omega-3 fatty acids and type 2 diabetes. We aim to evaluate the causal effect of omega-3 fatty acids on
Chunyan Hu, Yulin Zhou, Xueyan Wu, Xiaojing Jia, Yuanyue Zhu, Ruizhi Zheng, Shuangyuan Wang, Lin Lin, Hongyan Qi, Hong Lin, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yu Xu, Yuhong Chen, Guang Ning, Maria-Carolina Borges, Weiqing Wang, Jie Zheng, Yufang Bi, Jieli Lu   +21 more
doaj   +1 more source

Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]

, 2018
The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core   +2 more sources

Visit-to-visit HbA1c variability is associated with aortic stiffness progression in participants with type 2 diabetes

Cardiovascular Diabetology, 2023
Background Glycemic variability plays an important role in the development of cardiovascular disease (CVD). This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic stiffness progression in participants
Qianhua Fang, Juan Shi, Jia Zhang, Ying Peng, Cong Liu, Xing Wei, Zhuomeng Hu, Lin Sun, Jie Hong, Weiqiong Gu, Weiqing Wang, Yifei Zhang   +11 more
doaj   +1 more source