Results 21 to 30 of about 1,841,015 (211)

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

open access: yes, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Peri-implant diseases and metabolic syndrome components: a systematic review [PDF]

open access: yes, 2018
OBJECTIVE: Metabolic syndrome (MetS) is defined as a spectrum of conditions associated with an increased risk of developing CVD and type 2 diabetes.
Letizia, C   +6 more
core   +1 more source

Assessment of selected food intake frequency in patients with type 1 diabetes treated with personal insulin pumps

open access: yesRoczniki Panstwowego Zakladu Higieny, 2019
Background. It has been established that in Type 1 Diabetes Mellitus (T1DM), regardless of the insulin therapy model used, diet and proper eating habits are still important in the treatment of the disease.
Sabina Krzyżowska   +5 more
doaj   +1 more source

Stronger association of triglyceride glucose index than the HOMA-IR with arterial stiffness in patients with type 2 diabetes: a real-world single-centre study

open access: yesCardiovascular Diabetology, 2021
Background The triglyceride-glucose index (TyG index) has been proposed as a simple and reliable alternative insulin resistance (IR) marker, while the homeostasis model assessment for IR (HOMA-IR) is the most frequently used index.
Shujie Wang   +8 more
doaj   +1 more source

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

open access: yes, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela   +3 more
core   +2 more sources

Physiological conditions influencing regenerative potential of stem cells [PDF]

open access: yes, 2016
Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele   +3 more
core   +1 more source

Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]

open access: yes, 2018
The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core   +2 more sources

CBP/p300 HAT maintains the gene network critical for β cell identity and functional maturity

open access: yesCell Death and Disease, 2021
Loss of β cell identity and functional immaturity are thought to be involved in β cell failure in type 2 diabetes. CREB-binding protein (CBP) and its paralogue p300 act as multifunctional transcriptional co-activators and histone acetyltransferases (HAT)
Linlin Zhang   +12 more
doaj   +1 more source

A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

open access: yesScientific Reports, 2017
Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of
Arwen W. Gao   +13 more
doaj   +1 more source

Evaluating the distinct pleiotropic effects of omega-3 fatty acids on type 2 diabetes mellitus: a mendelian randomization study

open access: yesJournal of Translational Medicine, 2023
Background Observational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between omega-3 fatty acids and type 2 diabetes. We aim to evaluate the causal effect of omega-3 fatty acids on
Chunyan Hu   +21 more
doaj   +1 more source

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