Results 101 to 110 of about 3,807,237 (401)
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha
Synthetic and Systems Biotechnology, 2022 Bio-manufacturing via microbial cell factory requires large promoter library for fine-tuned metabolic engineering. Ogataea polymorpha, one of the methylotrophic yeasts, possesses advantages in broad substrate spectrum, thermal-tolerance, and capacity to ...
Chunxiao Yan +6 more
doaj
Fast computation of gradient and sentitivity in 13C metabolic flux analysis instationary experiments using the adjoint method [PDF]
arXiv, 2012 Metabolic flux analysis using 13C labeled substrates is an important tool for metabolic engineering. Although it has now been evolving for more than ten years, metabolic flux analysis has still not reached the limits of its application. First and foremost, there is only one reference software for the analysis and identification of metabolic fluxes ...
arxiv
Division of Metabolic Engineering [PDF]
, 2008 この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
Ali MahmoudEl-Halawany +3 more
core +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering [PDF]
, 2019 Industrial plant biotechnology applications include the production of sustainable fuels, complex metabolites and recombinant proteins, but process development can be impaired by a lack of reliable and scalable screening methods. Here, we describe a rapid
Arfi +28 more
core +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Synthetic and Systems Biotechnology, 2018 Advances in metabolic engineering and synthetic biology have facilitated the manufacturing of many valuable-added compounds and commodity chemicals using microbial cell factories in the past decade.
Lihong Jiang +3 more
doaj
Metabolic Engineering Communications, 2022 Hemicellulose is the second most abundant carbohydrate in lignocellulosic biomass and has extensive applications. In conventional biomass refinery, hemicellulose is easily converted to unwanted by-products in pretreatment and therefore can't be fully ...
Biao Geng +3 more
doaj
Metabolic engineering of microorganisms for production of aromatic compounds
Microbial Cell Factories, 2019 Metabolic engineering has been enabling development of high performance microbial strains for the efficient production of natural and non-natural compounds from renewable non-food biomass.
D. Huccetogullari, Z. Luo, S. Lee
semanticscholar +1 more source