Results 141 to 150 of about 574,220 (331)

Development of metabolic engineering. Production of useful compound by functional change in microorganism secondary metabolite biosynthesis.

, 1996
Haruo Ikeda
openalex   +2 more sources

Systems biology, bioinformatics and metabolic engineering [PDF]

, 2009
This research line covers the topics of genome-scale metabolic model re-construction, biological text mining and metabolic engineering with the ultimate aims of designing improved cell factories for the application in industrial biotechnology processes
Ferreira, E. C., Lourenço, Anália, Rocha, I., Soons, Zita   +3 more
core  

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

Harnessing the optimization of enzyme catalytic rates in engineering of metabolic phenotypes.

PLoS Computational Biology
The increasing availability of enzyme turnover number measurements from experiments and of turnover number predictions from deep learning models prompts the use of these enzyme parameters in precise metabolic engineering.
Zahra Razaghi-Moghadam, Fayaz Soleymani Babadi, Zoran Nikoloski   +2 more
doaj   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Editorial: Synthetic Biology-Guided Metabolic Engineering

Frontiers in Bioengineering and Biotechnology, 2020
Rodrigo Ledesma-Amaro, Rodrigo Ledesma-Amaro, Pablo I. Nikel, Francesca Ceroni, Francesca Ceroni   +4 more
doaj   +1 more source

Metabolic engineering as therapy for inborn errors of metabolism – development of mice with phenylalanine hydroxylase expression in muscle

, 1998
CO Harding, Krzysztof Wild, David Chang, Albee Messing, JA Wolff   +4 more
openalex   +1 more source

New Directions in Carbohydrate Engineering: A Metabolic Substrate-Based Approach to Modify the Cell Surface Display of Sialic Acids [PDF]

, 2001
Kevin J. Yarema
openalex   +1 more source

Nitric oxide‐forming nitrite reductases in the anaerobic ammonium oxidizer Kuenenia stuttgartiensis

FEBS Open Bio, EarlyView.
Anammox bacteria remove fixed nitrogen from their environment via anaerobic ammonium oxidation (anammox) with nitrite as electron acceptor and dinitrogen gas as product. The first anammox step is the conversion of nitrite to nitric oxide by nitrite reductase.
Femke J. Vermeir, Lotte W. Nijman, Robert S. Jansen, Laura van Niftrik, Wouter Versantvoort   +4 more
wiley   +1 more source