Results 191 to 200 of about 632,889 (322)

Metabolic engineering of Escherichia coli to high efficient synthesis phenylacetic acid from phenylalanine [PDF]

, 2017
Lihua Zhang, Qian Liu, Hong Pan, Xun Li, Daoyi Guo   +4 more
openalex   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Metabolic engineering for improved heterologous pinene production in the chloroplast of Phaeodactylum tricornutum. [PDF]

Microb Cell Fact
Trevisan N, van der Oost J, Barbosa M, D'Adamo S.   +3 more
europepmc   +1 more source

Metabolic and Process Engineering of Pichia Pastoris for the Production of Value-added Products

, 2017
Zhiliang Yang
openalex   +2 more sources

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

High-yield production of hydroxytyrosol through metabolic engineering of <i>Yarrowia lipolytica</i>. [PDF]

Synth Syst Biotechnol
Chen B, Wang Y, Wang D, Wang Y, Liu X, Zhang G, Yang S.   +6 more
europepmc   +1 more source

Metabolic engineering [PDF]

Nature Biotechnology, 2000
openaire   +2 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Metabolic engineering in <i>Nicotiana benthamiana</i>. [PDF]

aBIOTECH
Kalalagh KF, Papon N, Courdavault V, van der Krol S, Kappers IF, Kashkooli AB.   +5 more
europepmc   +1 more source

Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis

Samuel Edward Hakim, Nancy Choudhary, Karan Malhotra, Jian Peng, Arne Bültemeier, Ahmed Arafa, Ronja Friedhoff, Maximilian Bauer, Jessica Eikenberg, Claus-Peter Witte, Marco Herde, Philipp Heretsch, Boas Pucker, Jakob Franke   +13 more
openalex   +1 more source