Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett +15 more
wiley +1 more source
Metabolic Engineering Strategy for <i>Bacillus subtilis</i> Producing MK-7. [PDF]
Wu S +6 more
europepmc +1 more source
Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera +6 more
wiley +1 more source
Metabolic engineering of Yarrowia lipolytica targeting bottlenecks to boost D-Pantothenic acid biosynthesis. [PDF]
Li XK +6 more
europepmc +1 more source
Bacterial‐Electrochemical Platform Utilizing a MXene‐Peptide Hydrogel
A peptide‐based fibrillar hydrogel incorporating MXene facilitates efficient electron delivery to intracellular recombinant [FeFe]‐hydrogenase enzyme in E. coli, enabling sustained bioelectrochemical H2 production without engineered exoelectrogenicity pathways.
Oren Ben‐Zvi +6 more
wiley +1 more source
Metabolic engineering enables <i>Escherichia coli</i> to grow on 1,3-propanediol. [PDF]
Poon NY, Sinskey AJ, Zhou K.
europepmc +1 more source
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Metabolic engineering and adaptive laboratory evolution enhance squalene production in <i>Yarrowia lipolytica</i>. [PDF]
Zhao QQ +10 more
europepmc +1 more source
Double‐Interpenetrating Composite Bioink for Multi‐Component 3D Bioprinting and Biofabrication
Marine‐polysaccharides‐derived double interpenetrating network hydrogel‐based bioink, combining the attributes of physical and ionic crosslinking, enables room‐temperature bioprinting of mechanically defined structures that can be handled and are cytocompatible.
Fabian Tribukait‐Riemenschneider +1 more
wiley +1 more source
Metabolic engineering of endogenous MEP pathway for enhanced lycopene production in <i>Escherichia coli</i>. [PDF]
Xu X +6 more
europepmc +1 more source

