Results 231 to 240 of about 632,889 (322)

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

Arthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Reconstructing the hydrogenobyrinic acid synthetic toolkit by combining cell-free systems and metabolic engineering. [PDF]

Synth Syst Biotechnol
Lv R, Kang Q, Wang J, Luo X, Zhang D.
europepmc   +1 more source

Metabolic Engineering, Natural Drug Resources [PDF]

, 2004
中村 憲夫, 宮代 博継, 服部 征雄, 横澤 隆子   +3 more
core   +1 more source

Comparison of DNA and RNA quantification methods suitable for parameter estimation in metabolic modeling of microorganisms [PDF]

, 2006
De Maeseneire, Sofie, De Mey, Marjan, Lequeux, Gaspard, Maertens, Jo, Soetaert, Wim, Vandamme, Erick   +5 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

High-level prodigiosin production in <i>Pseudomonas putida</i> enabled by combinatorial metabolic engineering. [PDF]

Synth Syst Biotechnol
Zhang Y, Wang M, Dou K, Zhang R, Wang C, Bian X, Si J, Niu G.   +7 more
europepmc   +1 more source

Biofuel production by metabolic engineering [PDF]

, 2014
Guirado Pueyo, Artur, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
core  

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Enzyme-constrained genome-scale model of Yarrowia lipolytica predicts growth-phase specific metabolic engineering targets. [PDF]

Appl Microbiol Biotechnol
De Biaggi JS, Park YK, Kerkhoven EJ, Ledesma-Amaro R, Lahtvee PJ.   +4 more
europepmc   +1 more source

Metabolism and growth in selections of mutant libraries; Modeling metabolic phenotypes and engineering sugar utilization in Escherichia coli

, 2014
A.E. de Groot
openalex   +1 more source