Results 291 to 300 of about 564,518 (330)

Computational biology predicts metabolic engineering targets for increased production of 103 valuable chemicals in yeast. [PDF]

Proc Natl Acad Sci U S A
Domenzain I, Lu Y, Wang H, Shi J, Lu H, Nielsen J.   +5 more
europepmc   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Metabolic Engineering of Komagataella phaffii for Xylose Utilization from Cellulosic Biomass. [PDF]

Molecules
Park J, Park S, Evelina G, Kim S, Jin YS, Chi WJ, Kim IJ, Kim SR.   +7 more
europepmc   +1 more source

OptFlux: a software for metabolic engineering [PDF]

, 2009
Evangelista, Pedro, Ferreira, E. C., Maia, Paulo, Nielsen, Jens, Patil, Kiran Raosaheb, Pinto, José P., Rocha, I., Rocha, Miguel   +7 more
core  

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Metabolic engineering of Glarea lozoyensis for high-level production of pneumocandin B₀. [PDF]

Synth Syst Biotechnol
Zhang X, Cheng S, Yang J, Lu L, Deng Z, Bian G, Liu T.   +6 more
europepmc   +1 more source

Section of Metabolic Engineering, Medicinal Resources [PDF]

, 2005
中村 憲夫, 宮代 博継, 服部 征雄, 横澤 隆子   +3 more
core   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Minimal cut sets in metabolic networks: from conceptual foundations to applications in metabolic engineering and biomedicine. [PDF]

Brief Bioinform
Klamt S, Zanghellini J, von Kamp A.
europepmc   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source