Results 311 to 320 of about 564,518 (330)
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Current Opinion in Biotechnology, 1994
Metabolic engineering is not another form of classic manipulation of intermediary metabolism; rather, it is the purposeful design of metabolic networks. The metabolic engineering approach examines biochemical reactions in their entirety, rather than individually, and is concerned with the construction of novel pathways, the thermodynamic feasibility of
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Metabolic engineering is not another form of classic manipulation of intermediary metabolism; rather, it is the purposeful design of metabolic networks. The metabolic engineering approach examines biochemical reactions in their entirety, rather than individually, and is concerned with the construction of novel pathways, the thermodynamic feasibility of
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2007
Metabolic engineering is a powerful methodology aimed at intelligently designing new biological pathways, systems, and ultimately phenotypes through the use of recombinant DNA technology. Built largely on the theoretical and computational analysis of chemical systems, the field has evolved to incorporate a growing number of genome scale experimental ...
R Michael, Raab +2 more
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Metabolic engineering is a powerful methodology aimed at intelligently designing new biological pathways, systems, and ultimately phenotypes through the use of recombinant DNA technology. Built largely on the theoretical and computational analysis of chemical systems, the field has evolved to incorporate a growing number of genome scale experimental ...
R Michael, Raab +2 more
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Metabolic Fluxes and Metabolic Engineering
Metabolic Engineering, 1999Metabolic engineering is the directed improvement of cellular properties through the modification of specific biochemical reactions or the introduction of new ones, with the use of recombinant DNA technology. As such, metabolic engineering emphasizes metabolic pathway integration and relies on metabolic fluxes as determinants of cell physiology and ...
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Engineering of Crassulacean Acid Metabolism
Annual Review of Plant Biology, 2021Crassulacean acid metabolism (CAM) has evolved from a C3ground state to increase water use efficiency of photosynthesis. During CAM evolution, selective pressures altered the abundance and expression patterns of C3genes and their regulators to enable the trait. The circadian pattern of CO2fixation and the stomatal opening pattern observed in CAM can be
Schiller, Katharina, Bräutigam, Andrea
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2011
Metabolic engineering is the intentional modification of cellular metabolism for the production of desired compounds. With the use of recombinant DNA technology, metabolic pathways of various organisms can be manipulated. Bacteria, fungi, plant, and animal cells are all used as host organisms, and selection is primarily driven by the properties of ...
S. Hou, K.H. Lee, D.M. Wuest
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Metabolic engineering is the intentional modification of cellular metabolism for the production of desired compounds. With the use of recombinant DNA technology, metabolic pathways of various organisms can be manipulated. Bacteria, fungi, plant, and animal cells are all used as host organisms, and selection is primarily driven by the properties of ...
S. Hou, K.H. Lee, D.M. Wuest
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Engineering the plant metabolic system by exploiting metabolic regulation
The Plant Journal, 2023SUMMARYPlants are the most sophisticated biofactories and sources of food and biofuels present in nature. By engineering plant metabolism, the production of desired compounds can be increased and the nutritional or commercial value of the plant species can be improved.
Selma, Sara +3 more
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Metabolic flux analysis and metabolic engineering of microorganisms
Mol. BioSyst., 2008Recent advances in metabolic flux analysis including genome-scale constraints-based flux analysis and its applications in metabolic engineering are reviewed. Various computational aspects of constraints-based flux analysis including genome-scale stoichiometric models, additional constraints used for the improved accuracy, and several algorithms for ...
Kim, Hyun Uk +2 more
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Metabolic Engineering of Photorespiration
2017The introduction of two alternative glycolate catabolic pathways in the chloroplasts of Arabidopsis thaliana rendered plants with increased biomass. To introduce these synthetic pathways, the selected genes were stepwise integrated in the nuclear genome of wild-type plants.
Veronica G. Maurino +1 more
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Engineering of Secondary Metabolism
Annual Review of Genetics, 2015Secondary (specialized) metabolites, produced by bacteria, fungi, plants, and other organisms, exhibit enormous structural variation, and consequently display a wide range of biological activities. Secondary metabolism improves and modulates the phenotype of the host producer.
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Application of Metabolic Flux Analysis in Metabolic Engineering
2011Metabolic flux analysis (MFA) is an important analytical technique to quantify intracellular metabolic fluxes as a consequence of all catalytic and transcriptional interactions. In systems metabolic engineering, MFA has played important role to understand cellular physiology under particular conditions and predict its metabolic capability after genetic
Lee, SY Lee, Sang-Yup +2 more
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