Results 121 to 130 of about 116,098 (154)

Seasonal transcriptomic shifts reveal metabolic flexibility of chemosynthetic symbionts in an upwelling region. [PDF]

open access: yesmSystems
Morel-Letelier I   +7 more
europepmc   +1 more source

Kdm2a inhibition in skeletal muscle improves metabolic flexibility in obesity. [PDF]

open access: yesNat Metab
Wang Y   +21 more
europepmc   +1 more source

Measuring Postprandial Metabolic Flexibility to Assess Metabolic Health and Disease

Journal of Nutrition, 2021
Metabolic abnormalities substantially increase the risk of noncommunicable diseases, which are among the leading causes of mortality globally. Mitigating and preventing these adverse consequences remains challenging due to a limited understanding of metabolic health. Metabolic flexibility, a key tenet of metabolic health, encompasses the responsiveness
Aryeh Stein, Elaine A Yu, Stein Aryeh D
exaly   +3 more sources

Pathophysiological role of metabolic flexibility on metabolic health

Obesity Reviews, 2020
SummaryGlucose, fatty acids, and amino acids among others are oxidized to generate adenosine triphosphate (ATP). These fuels are supplied from the environment (through food intake) and internal depots (through lipolysis, glycogenolysis, and proteolysis) at different rates throughout the day. Complex adaptive systems permit to accommodate fuel oxidation
Jose E. Galgani   +1 more
openaire   +3 more sources

Metabolic (In)Flexibility of the Diabetic Heart

Cardiovascular Drugs and Therapy, 2008
Metabolic inflexibility was first described as a failure of skeletal muscle of diabetic subjects to appropriately move between use of lipid in the fasting state and use of carbohydrate in the insulin-stimulated prandial state. Metabolically healthy hearts have a well developed capacity to switch between lipid and carbohydrate fuels, depending on ...
Terje S, Larsen, Ellen, Aasum
openaire   +2 more sources

Circadian rhythms in cardiac metabolic flexibility

Chronobiology International, 2021
Numerous aspects of cardiovascular physiology (e.g., heart rate, blood pressure) and pathology (e.g., myocardial infarction and sudden cardiac death) exhibit time-of-day-dependency. In association with day-night differences in energetic demand and substrate availability, the healthy heart displays remarkable metabolic flexibility through temporal ...
Martin E. Young, Mary N. Latimer
openaire   +2 more sources

Metabolic Flexibility and Morphological Plasticity in Mycobacteria

Future Microbiology, 2015
10.2217/fmb.14.151 ; Future Microbiology ; 10 ; 4 ; 449 ...
Wu M.-L, Dick T
openaire   +2 more sources

Latitudinal Patterns in Rodent Metabolic Flexibility

The American Naturalist, 2012
Macrophysiology is defined as the study of variation in physiological traits-including physiological trait flexibility-over large geographical and temporal scales, and the ecological implications of this variation. A classic example of a macrophysiological trend is the one emerging from the climatic variability hypothesis, which states that as the ...
Daniel E, Naya   +3 more
openaire   +3 more sources

Neuronal metabolism: Surprisingly flexible

Current Biology
Neuronal function is costly and depends on efficient metabolism. Thus, metabolic perturbation is thought to be detrimental for neuronal function and contributes to the development of neurodegeneration. A study now shows that this is not necessarily the case and that neurons are capable of substantial metabolic rearrangement.
Andrés, Köhler-Solís   +1 more
openaire   +2 more sources

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