Results 201 to 210 of about 1,689,302 (242)

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Metabolic flexibility and reverse remodelling of the failing human heart. [PDF]

Eur Heart J
Green PG, Watson WD, Bussmann BM, De Maria GL, Neubauer S, Lewis AJM, Rider OJ, Herring N.   +7 more
europepmc   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

Advanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu, Hanxiao Chen, Qichen Yuan, Liucun Yin, Yifang Tao, Hong Wang, Yuquan Xue, Delai Fu, Huan Pang, Tie Chong, Li Xue   +10 more
wiley   +1 more source

Spermidine enhances metabolic flexibility and attenuates inflammation associated with ageing in farmed Atlantic salmon

Phadwal K, Kurian D, Haggarty J, Migaud H, Nicheva V, Dick J, Salamat MKF, Whitfield PD, Matthew C, Wade NM, Betancor MB, Macqueen DJ.   +11 more
europepmc   +1 more source

Successfully Reducing Sitting Time Can Improve Metabolic Flexibility. [PDF]

Scand J Med Sci Sports
Garthwaite T, Sjöros T, Laine S, Koivumäki M, Vähä-Ypyä H, Norha J, Kallio P, Saarenhovi M, Löyttyniemi E, Sievänen H, Houttu N, Laitinen K, Kalliokoski KK, Vasankari T, Knuuti J, Heinonen I.   +15 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Commentary on “Are Individuals With Type 2 Diabetes Metabolically Inflexible? A Systematic Review and Meta‐Analysis”

Endocrinology, Diabetes & Metabolism
Katerina Koudelkova, Cedric Moro, Jan Gojda   +2 more
doaj   +1 more source

The mevalonate pathway of isoprenoid biosynthesis supports metabolic flexibility in <i>Mycobacterium marinum</i>. [PDF]

J Bacteriol
Qabar CM, Baidoo EE, Akyuz Turumtay E, Qayum TM, Keasling JD, Madigan CA, Portnoy DA, Cox JS.   +7 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Time-restricted feeding improves metabolic flexibility, promotes beiging, and mitigates fibro-inflammation in the adipose tissue of aged mice. [PDF]

J Gerontol A Biol Sci Med Sci
Natarajan D, Milan M, Reyff Z, Negri S, Ekambaram S, Varshney RR, Rudolph MC, Tarantini S, Balasubramanian P.   +8 more
europepmc   +1 more source