Results 241 to 250 of about 2,044,373 (297)

Phytochemical profiling, network pharmacology, and molecular dynamics simulations of <i>Sinularia levi</i> metabolites as potential α-glucosidase inhibitors in metabolic syndrome. [PDF]

RSC Adv
Mahmoud BK, Samy MN, Les F, Abou-Zied HA, Mostafa NM, Madkour HA, Hamed EAE, Rateb ME, Abdelmohsen UR, Elkhouly HB.   +9 more
europepmc   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Rumen Microbiota, Predicted Metabolic Pathways, and Fermentation Parameters Exhibit Production-System-Specific Associations in Cattle and Goats. [PDF]

Microorganisms
Cui C, Zheng Y, Guo Z, Wang Z, Zhu X, Cui Y, Li D, Chen W, Shi Y, Liu B.   +9 more
europepmc   +1 more source

Adenosine 5'-Carboxamide-Based Inhibitors of METTL1. [PDF]

ACS Med Chem Lett
Bobileva O, Nai F, Niedrite S, Mayordomo Soler L, Leite I, Caflisch A.   +5 more
europepmc   +1 more source

Empagliflozin Targets NF-κB Signaling Through PTGS2 and TLR4 in Polycystic Ovary Syndrome: A Drug Repurposing Study and Molecular Simulation. [PDF]

J Xenobiot
Nugraha IC, Febriza A, Tajuddin A, As'ad S.   +3 more
europepmc   +1 more source

Molecular and metabolic mechanisms of quercetin in liver fibrosis: an integrated network pharmacology, metabolomics, and molecular dynamics study. [PDF]

Front Pharmacol
Song X, Guo T, Li Y, Liu J, Niu S, Zheng D, Xue H, Sun J, Bai F, Wang Z, Bai W.   +10 more
europepmc   +1 more source

Dietary Sulfur Compounds and Halitosis: Bridging Food Science, Microbial Metabolism, and Oral Health: A Comprehensive Review. [PDF]

Mol Nutr Food Res
Acheampong R, Otu-Ayeboafo JO.
europepmc   +1 more source

Musculoskeletal Disorders: From Molecular Pathology to Novel Therapeutic Approach. [PDF]

Int J Mol Sci
Lucha-López MO.
europepmc   +1 more source