Results 71 to 80 of about 2,044,373 (297)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Technical assessment of green hydrogen production in Kuwait [PDF]

Kuwait has the potential to produce green hydrogen from renewable energy. Hydrogen production is receiving increased attention and has become a core research area.
Alhajeri, A, Ghazal, H, Jouhara, H, Olabi, V   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Hydrogen Sulfide: Redox Metabolism and Signaling [PDF]

Antioxidants & Redox Signaling, 2011
The recognition of hydrogen sulfide (H(2)S) as an endogenously produced gas with signaling potential has stimulated research on a multitude of physiological effects mediated in the cardiovascular, immune, gastrointestinal, genitourinary, endocrine, and central nervous systems. The heightened activity in the area of H(2)S biology led to convening of the
openaire   +3 more sources

Hydrogen Production with Membrane Systems

, 2017
It is well-known that hydrogen is conventionally produced via reforming of fossil fuels in large-scale plants. Apart from small-scale hydrogen production from renewable energy sources (mostly using electricity from renewable sources), more than 80% of ...
E. Fernandez, A. Arratibel, Pacheco Tanaka, D.A., F. Gallucci, D.A. Pacheco Tanaka, Gallucci, F., Gallucci, F.; id_orcid, Medrano, J., Annaland, M. V.Sint, J.A. Medrano, van Sint Annaland, Martin, Arratibel, A., M.v. Sint Annaland, Tanaka, D. A.Pacheco, Fernandez, E.   +14 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Demystifying Hydrogen: Victorian Hydrogen Hub (VH2) Hydrogen Readiness Program

, 2022
Brought to you by Swinburne University of Technology’s Victorian Hydrogen Hub (VH2), the ‘Hydrogen Readiness Program’ incorporates the scientifically approved facts about hydrogen and hydrogen technologies into a logical and easy-to-understand webinar ...
Gordon Chakaodza, Dr Daniel Roberts, Dr Jason Zheng   +2 more
core   +1 more source

Preparation, testing and modelling of a hydrogen selective Pd/YSZ/SS composite membrane

, 2011
A palladium selective tubular membrane has been prepared to separate and purify hydrogen. The membrane consists of a composite material, formed by different layers: a stainless steel support (thickness of 1.9 mm), an yttria-stabilized zirconia interphase
D. Alique, E. Fernandez, Fernández Gesalaga, Ekain, Marín González, Pablo, Marín, P., Corengia Cabrera, Pablo, Sanz Martín, Raúl, R. Sanz, P. Corengia, Fernandez, E., P. Marín, Ordóñez, S., Ordóñez García, Salvador, Furones, L., Calles, J. A., L. Furones, S. Ordóñez, Alique, D., Calles Martín, José Antonio, Calles, J.A., J.A. Calles, Alique Amor, David, Sanz, R., Corengia, P., Furones Martínez, Laura   +24 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Molecular mechanisms associated with effects of hydrogen molecule in liver diseases: the review of current evidence

European Journal of Medical Research
Oxidative stress and inflammation play a key role in the occurrence and progression of liver diseases, inducing hepatocyte apoptosis, fibrosis, and even cancer.
Qian Zhu, Xianzhi Li, Shiyang Li, Shunjin Liu, Yunyun Tian, Xiangyi Xing, Li Yin   +6 more
doaj   +1 more source