Results 251 to 260 of about 450,408 (297)

Modelling amino acid metabolism

Amino Acids, 1992
This article briefly summarises various aspects of building a model, before reviewing some models of protein turnover, the metabolism of selected amino acids, and urea synthesis in human subjects. Some software for use in modelling is noted. An Appendix lists terms with descriptions and definitions, which are often employed in modelling.
M, Hjelm, J, Seakins
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Metabolic theory or metabolic models?

Trends in Ecology & Evolution, 2008
The metabolic theory of ecology (MTE) claims to derive ecological relationships from the structure of resource distribution networks, which is assumed to determine the scaling of metabolism with body mass, and from the effect of temperature on the rate of biological processes. MTE is controversial.
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Kinetic Models of Metabolism

Nuklearmedizin, 1986
The model structure established here can be applied to tracer kinetics, pharmacokinetics and to non-equilibrium responses. Furthermore the possible and impossible pathways of metabolism can be determined directly leading to a special model version corresponding to a special kinetic problem.
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Modelling Metabolic Networks—The Theories of Metabolism

2013
Abstract There are several theoretical approaches to metabolism. Some of them give a greater place to the structure of the metabolic network symbolized by its stoichiometry matrix. The constraints in a metabolic network are very strong so that a lot of information can be derived from the stoichiometry matrix without any knowledge of the kinetic ...
Mazat, Jean-Pierre, Beauvoit, Bertrand
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Microbial Models of Mammalian Metabolism

Journal of Natural Products, 1975
A solid basis for the M4-approach has been developed over the past 10 years. Recent examples of the production of difficult-to-synthesize mammalian metabolites through microbial transformations attest to the utility of the methodology. There is, however, much more to be done.
R V, Smith, J P, Rosazza
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Modelling Inulin Metabolism

1993
ABSTRACT We have modelled the distribution of chain lengths of the inulin accumulated in the storage organs of species belonging to the Compositae. Our analysis reveals that the relative abundance of chain lengths can be shown to depend on the relative affinity for different chain lengths of the enzyme responsible for the reversible ...
M.W. SHAW, K. LODGE, P. JOHN
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ScrumPy: metabolic modelling with Python

IEE Proceedings - Systems Biology, 2006
ScrumPy is a software package used for the definition and analysis of metabolic models. It is written using the Python programming language that is also used as a user interface. ScrumPy has features for both kinetic and structural modelling, but the emphasis is on structural modelling and those features of most relevance to analysis of large (genome ...
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Metabolic Models of Selection Response

Journal of Theoretical Biology, 1996
Consequences of directional selection on metabolic flux are explored in models for which variation in flux among individuals is generated by segregation of allelic variants at enzyme activity loci. The pattern of selection response is strongly affected by the presence of genetic dominance and epistasis, which are automatically generated in metabolic ...
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Bile acids and the gut microbiota: metabolic interactions and impacts on disease

Nature Reviews Microbiology, 2022
Stephanie Collins, Andrew D Patterson
exaly  

Microbial Models for Drug Metabolism

1999
This review describes microbial transformation studies of drugs, comparing them with the corresponding metabolism in animal systems, and providing technical methods for developing microbial models. Emphasis is laid on the potential for selected microorganisms to mimic all patterns of mammalian biotransformations and to provide preparative methods for ...
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