Results 41 to 50 of about 911,565 (297)
Modeling cancer metabolism on a genome scale [PDF]
, 2015 Cancer cells have fundamentally altered cellular metabolism that is associated with their tumorigenicity and malignancy. In addition to the widely studied Warburg effect, several new key metabolic alterations in cancer have been established over the last
Barbara Chaneton +8 more
core +1 more source
Altered Metabolic Networks in Mesial Temporal Lobe Epilepsy with Focal to Bilateral Seizures
Brain Sciences, 2023 This study was designed to identify whether the metabolic network changes in mesial temporal lobe epilepsy (MTLE) patients with focal to bilateral tonic-clonic seizures (FBTCS) differ from changes in patients without FBTCS.
Zhihao Guo +7 more
doaj +1 more source
Body mass index dependent metabolic syndrome in severe mental illness patients [PDF]
, 2015 The aim of this study was to evaluate the body mass index dependent metabolic syndrome in severe mental illness patients in Gorgan. A total of 267 severe mental illness patients took part in this study.
Aliakbari Zaman Kamkar, F.M. +1 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Detecting degree symmetries in networks [PDF]
, 2006 The surrounding of a vertex in a network can be more or less symmetric. We derive measures of a specific kind of symmetry of a vertex which we call degree symmetry -- the property that many paths going out from a vertex have overlapping degree sequences.
Petter Holme +4 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Biomolecules, 2023 Background: Whole-genome models (GEMs) have become a versatile tool for systems biology, biotechnology, and medicine. GEMs created by automatic and semi-automatic approaches contain a lot of redundant reactions.
Anatoly Sorokin, Igor Goryanin
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Environmental and genetic perturbations reveal different networks of metabolic regulation
Molecular Systems Biology, 2011 Progress in systems biology depends on accurate descriptions of biological networks. Connections in a regulatory network are identified as correlations of gene expression across a set of environmental or genetic perturbations.
Anthony J Greenberg +3 more
doaj +1 more source
Branching process approach for Boolean bipartite networks of metabolic reactions
, 2012 The branching process (BP) approach has been successful in explaining the avalanche dynamics in complex networks. However, its applications are mainly focused on unipartite networks, in which all nodes are of the same type.
B. Kahng +3 more
core +1 more source