Results 61 to 70 of about 898,161 (347)

Semantics of Dairy Fermented Foods: A Microbiologist’s Perspective

Foods, 2022
Food ontologies are acquiring a central role in human nutrition, providing a standardized terminology for a proper description of intervention and observational trials.
Francesco Vitali, Paola Zinno, Emily Schifano, Agnese Gori, Ana Costa, Carlotta De Filippo, Barbara Koroušić Seljak, Panče Panov, Chiara Devirgiliis, Duccio Cavalieri   +9 more
doaj   +1 more source

Signatures of currency vertices

, 2008
Many real-world networks have broad degree distributions. For some systems, this means that the functional significance of the vertices is also broadly distributed, in other cases the vertices are equally significant, but in different ways.
Albert R., Arita M., Buckley F., Caldarelli G., Ebel H., Gleiser P., Guimerà R., Guimerà R., Guimerà R., Holme P., Holme P., Holme P., Huss M., Lusseau D., Ma H.-W., Maslov S., Newman M. E. J., Newman M. E. J., Newman M. E. J., Newman M. E. J., Rosvall M., Solé R. V., Wagner A., Wasserman S., White J. G., Zhao J., Zhao J.   +26 more
core   +1 more source

Metabolic network percolation quantifies biosynthetic capabilities across the human oral microbiome [PDF]

, 2019
The biosynthetic capabilities of microbes underlie their growth and interactions, playing a prominent role in microbial community structure. For large, diverse microbial communities, prediction of these capabilities is limited by uncertainty about ...
Bernstein, David B., Dewhirst, Floyd E., Segrè, Daniel   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Elasticity sampling links thermodynamics to metabolic control

, 2013
Metabolic networks can be turned into kinetic models in a predefined steady state by sampling the reaction elasticities in this state. Elasticities for many reversible rate laws can be computed from the reaction Gibbs free energies, which are determined ...
Liebermeister, Wolfram
core   +2 more sources

Randomizing Genome-Scale Metabolic Networks

PLoS ONE, 2011
Networks coming from protein-protein interactions, transcriptional regulation, signaling, or metabolism may appear to have "unusual" properties. To quantify this, it is appropriate to randomize the network and test the hypothesis that the network is not statistically different from expected in a motivated ensemble.
Samal, Areejit, Martin, Olivier C.
openaire   +7 more sources

Alteration of the Individual Metabolic Network of the Brain Based on Jensen-Shannon Divergence Similarity Estimation in Elderly Patients With Type 2 Diabetes Mellitus [PDF]

, 2022
Yulin Li, Jia‐Jia Wu, Jie Ma, Sisi Li, Xin Xue, Wei Dong, Chunlei Shan, Xu‐Yun Hua, Mou‐Xiong Zheng, Jian‐Guang Xu   +9 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

TSC22D4 is a molecular output of hepatic wasting metabolism

EMBO Molecular Medicine, 2013
In mammals, proper storage and distribution of lipids in and between tissues is essential for the maintenance of energy homeostasis. Here, we show that tumour growth triggers hepatic metabolic dysfunction as part of the cancer cachectic phenotype ...
Allan Jones, Kilian Friedrich, Maria Rohm, Michaela Schäfer, Carolyn Algire, Philipp Kulozik, Oksana Seibert, Karin Müller‐Decker, Tjeerd Sijmonsma, Daniela Strzoda, Carsten Sticht, Norbert Gretz, Geesje M. Dallinga‐Thie, Barbara Leuchs, Manfred Kögl, Wolfgang Stremmel, Mauricio Berriel Diaz, Stephan Herzig   +17 more
doaj   +1 more source

Sirtuins as regulators of the yeast metabolic network

Frontiers in Pharmacology, 2012
There is growing evidence that the metabolic network is an integral regulator of cellularphysiology. Dynamic changes in metabolite concentrations, metabolic flux, or networktopology act as reporters of biological or environmental signals, and are ...
Markus eRalser, Markus eRalser, Steve eMichel, Michael eBreitenbach   +3 more
doaj   +1 more source