Results 321 to 330 of about 335,580 (367)

Pain induces a rapid characteristic metabolic signature detectable in breath

open access: yes
Sinues P   +12 more
europepmc   +1 more source

Prediction of metabolic pathways from genome-scale metabolic networks

Biosystems, 2011
The analysis of a variety of data sets (transcriptome arrays, phylogenetic profiles, etc.) yields groups of functionally related genes. In order to determine their biological function, associated gene groups are often projected onto known pathways or tested for enrichment of known functions.
Faust, Karoline   +2 more
openaire   +6 more sources

Inferring Meaningful Pathways in Weighted Metabolic Networks

Journal of Molecular Biology, 2006
An approach is presented for computing meaningful pathways in the network of small molecule metabolism comprising the chemical reactions characterized in all organisms. The metabolic network is described as a weighted graph in which all the compounds are included, but each compound is assigned a weight equal to the number of reactions in which it ...
Jacques van Helden   +4 more
openaire   +5 more sources

Pathway knockout and redundancy in metabolic networks

Journal of Theoretical Biology, 2011
The robustness and stability of complex cellular networks is often attributed to the redundancy of components, including genes, enzymes and pathways. Estimation of redundancy is still an open question in systems biology. Current theoretical tools to measure redundancy have various strengths and shortcomings in providing a comprehensive description of ...
Zhengzheng Pan   +5 more
openaire   +3 more sources

Predicting Metabolic Pathways by Sub-network Extraction [PDF]

open access: possible, 2011
Various methods result in groups of functionally related genes obtained from genomes (operons, regulons, syntheny groups, and phylogenetic profiles), transcriptomes (co-expression groups) and proteomes (modules of interacting proteins). When such groups contain two or more enzyme-coding genes, graph analysis methods can be applied to extract a ...
Faust, Karoline, van Helden, Jacques
openaire   +4 more sources

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