Results 11 to 20 of about 972,456 (315)

Metabolic pathway engineering

open access: yesSynthetic and Systems Biotechnology, 2018
Hal S. Alper
doaj   +3 more sources

Alignment of metabolic pathways [PDF]

open access: yesBioinformatics, 2005
Several genome-scale efforts are underway to reconstruct metabolic networks for a variety of organisms. As the resulting data accumulates, the need for analysis tools increases. A notable requirement is a pathway alignment finder that enables both the detection of conserved metabolic pathways among different species as well as divergent metabolic ...
Ron Y. Pinter   +3 more
openaire   +2 more sources

Systematic assignment of thermodynamic constraints in metabolic network models [PDF]

open access: yes, 2006
Background: The availability of genome sequences for many organisms enabled the reconstruction of several genome-scale metabolic network models. Currently, significant efforts are put into the automated reconstruction of such models.
Kümmel, Anne,   +12 more
core   +1 more source

Production of C2–C4 diols from renewable bioresources: new metabolic pathways and metabolic engineering strategies

open access: yesBiotechnology for Biofuels, 2017
C2–C4 diols classically derived from fossil resource are very important bulk chemicals which have been used in a wide range of areas, including solvents, fuels, polymers, cosmetics, and pharmaceuticals.
Ye Zhang, Dehua Liu, Zhen Chen
doaj   +1 more source

Kinetics and New Mechanism of Azoxystrobin Biodegradation by an Ochrobactrum anthropi Strain SH14

open access: yesMicroorganisms, 2020
Azoxystrobin is one of the most popular strobilurin fungicides, widely used in agricultural fields for decades.Extensive use of azoxystrobin poses a major threat to ecosystems.
Yanmei Feng   +7 more
doaj   +1 more source

Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine [PDF]

open access: yes, 2012
Background: Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism.
Sarah Zimmet   +11 more
core   +1 more source

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

open access: yesMolecules, 2017
Aberrant metabolism is one of the main driving forces in the initiation and development of ESCC. Both genes and metabolites play important roles in metabolic pathways. Integrative pathway analysis of both genes and metabolites will thus help to interpret
Chunquan Li   +6 more
doaj   +1 more source

Identification of Metabolic Pathway Systems

open access: yesFrontiers in Genetics, 2016
The estimation of parameters in even moderately large biological systems is a significant challenge. This challenge is greatly exacerbated if the mathematical formats of appropriate process descriptions are unknown.
Sepideh eDolatshahi, Eberhard Otto Voit
doaj   +1 more source

Metabolic Pathways of Acylcarnitine Synthesis

open access: yesPhysiological Research, 2023
Acylcarnitines are important markers in metabolic studies of many diseases, including metabolic, cardiovascular, and neurological disorders. We reviewed analytical methods for analyzing acylcarnitines with respect to the available molecular structural information, the technical limitations of legacy methods, and the potential of new mass spectrometry ...
Jana Brejchova   +2 more
openaire   +3 more sources

Databases of metabolic pathways [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2006
AbstractStudies of metabolism usually evoke memories of densely written wall charts of metabolic pathways of enormous complexity, such as the IUBMB‐Nicholson metabolic pathways map or the Roche metabolic pathways wall chart. Advances in bioinformatics in the past decade have brought about a revolution in the way the information in metabolic pathways is
openaire   +2 more sources

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