Results 21 to 30 of about 1,447,822 (302)

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background The amino acid response (AAR) is an evolutionarily conserved protective mechanism activated by amino acid deficiency through a key kinase, general control nonderepressible 2.
Pu Qin   +31 more
doaj   +1 more source

Elementary vectors and conformal sums in polyhedral geometry and their relevance for metabolic pathway analysis [PDF]

open access: yes, 2016
A fundamental result in metabolic pathway analysis states that every flux mode can be decomposed into a sum of elementary modes. However, only a decomposition without cancelations is biochemically meaningful, since a reversible reaction cannot have ...
Müller, Stefan, Regensburger, Georg
core   +3 more sources

The metabolomics variations among rice, brown rice, wet germinated brown rice, and processed wet germinated brown rice

open access: yesJournal of Integrative Agriculture, 2022
Germination and processing are always accompanied by significant changes in the metabolic compositions of rice. In this study, polished rice (rice), brown rice, wet germinated brown rice (WGBR), high temperature and pressure-treated WGBR (WGBR-HTP), and ...
Chuan-ying REN   +8 more
doaj   +1 more source

Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]

open access: yes, 2019
One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
core   +1 more source

Production of C2–C4 diols from renewable bioresources: new metabolic pathways and metabolic engineering strategies

open access: yesBiotechnology for Biofuels, 2017
C2–C4 diols classically derived from fossil resource are very important bulk chemicals which have been used in a wide range of areas, including solvents, fuels, polymers, cosmetics, and pharmaceuticals.
Ye Zhang, Dehua Liu, Zhen Chen
doaj   +1 more source

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]

open access: yes, 2012
Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M.   +8 more
core   +2 more sources

Kinetics and New Mechanism of Azoxystrobin Biodegradation by an Ochrobactrum anthropi Strain SH14

open access: yesMicroorganisms, 2020
Azoxystrobin is one of the most popular strobilurin fungicides, widely used in agricultural fields for decades.Extensive use of azoxystrobin poses a major threat to ecosystems.
Yanmei Feng   +7 more
doaj   +1 more source

Metabolic Modulation Predicts Heart Failure Tests Performance [PDF]

open access: yes, 2019
The metabolic changes that accompany changes in Cardiopulmonary testing (CPET) and heart failure biomarkers (HFbio) are not well known. We undertook metabolomic and lipidomic phenotyping of a cohort of heart failure (HF) patients and utilized Multiple ...
Abbate, Antonio   +11 more
core   +3 more sources

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

open access: yesMolecules, 2017
Aberrant metabolism is one of the main driving forces in the initiation and development of ESCC. Both genes and metabolites play important roles in metabolic pathways. Integrative pathway analysis of both genes and metabolites will thus help to interpret
Chunquan Li   +6 more
doaj   +1 more source

Improving clustering with metabolic pathway data [PDF]

open access: yes, 2014
Background: It is a common practice in bioinformatics to validate each group returned by a clustering algorithm through manual analysis, according to a-priori biological knowledge.
Carrari, Fernando Oscar   +4 more
core   +2 more sources

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