Metabolic Regulation Mechanism of <i>Ilex verticillata</i> in Response to Drought Stress: "First Inhibition Then Promotion" of Lipids and the Key Mediation of Glycerophospholipid Metabolic Pathway. [PDF]
Xue Y, Cheng Y, Li Q, Xing E, Yan D.
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Feeding regimens reshape rumen microbiota and metabolome in Shorthorn cattle: a multi-omic insight into microbial diversity and metabolic pathway dynamics. [PDF]
Dai S, He S, Zhao S, Li Q, Mao H, Wu D.
europepmc +1 more source
Conserved function of a
Orsolya Sárkány +6 more
openalex +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
SNP associations in the L-citrulline metabolic pathway and vascular aging in the Japanese population. [PDF]
Nogimura D +5 more
europepmc +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
One-carbon metabolic pathway is a novel molecular signature for CD44-positive intestinal-type gastric cancer. [PDF]
Joo S +8 more
europepmc +1 more source

