Results 241 to 250 of about 1,447,822 (302)

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Methodologies to Identify Metabolic Pathway Differences Between Emaciated and Moderately Conditioned Horses: A Review of Multiple Gene Expression Techniques. [PDF]

Animals (Basel)
Austin MMP, Ivey JLZ, Shepherd EA, Myer PR.   +3 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

SNP associations in the L-citrulline metabolic pathway and vascular aging in the Japanese population. [PDF]

PLoS One
Nogimura D, Moriyasu K, Ishida S, Kohda M, Yazawa T, Morita M.   +5 more
europepmc   +1 more source

Key Components of PPEO in Antagonizing Cerebral Ischemic Reperfusion Injury in Rats by Regulating Ferroptosis Through Arachidonic Acid Metabolic Pathway. [PDF]

Curr Issues Mol Biol
Du Z, Huang F, Liang Y, Xie L, Hu W.
europepmc   +1 more source

Feeding regimens reshape rumen microbiota and metabolome in Shorthorn cattle: a multi-omic insight into microbial diversity and metabolic pathway dynamics. [PDF]

Front Microbiol
Dai S, He S, Zhao S, Li Q, Mao H, Wu D.
europepmc   +1 more source

Metabolic Regulation Mechanism of <i>Ilex verticillata</i> in Response to Drought Stress: "First Inhibition Then Promotion" of Lipids and the Key Mediation of Glycerophospholipid Metabolic Pathway. [PDF]

Biology (Basel)
Xue Y, Cheng Y, Li Q, Xing E, Yan D.
europepmc   +1 more source

One-carbon metabolic pathway is a novel molecular signature for CD44-positive intestinal-type gastric cancer. [PDF]

Cell Death Discov
Joo S, Bae Y, Yoon BK, Je Y, Kim Y, Kim M, Shin SJ, Fang S, Kim JH.   +8 more
europepmc   +1 more source

The 12-LOX/12-HETE/GPR31 metabolic pathway promotes tumor-associated macrophage M2 polarization mediated pancreatic cancer development. [PDF]

PeerJ
Yang Y, Wang Y, Wu J, Tan C, Huang L.
europepmc   +1 more source