Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
Genetic mechanism of β-alanine metabolic pathway affecting colorectal cancer prognosis. [PDF]
Zhao T +7 more
europepmc +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
An expanded metabolic pathway for androgen production by commensal bacteria. [PDF]
Wang T +27 more
europepmc +1 more source
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij +11 more
wiley +1 more source
Integrated Metabolomics and Transcriptomics Reveals Metabolic Pathway Changes in Common Carp Muscle Under Oxidative Stress. [PDF]
Liu Y +8 more
europepmc +1 more source
Inter-Relationship Between Melanoma Vemurafenib Tolerance Thresholds and Metabolic Pathway Choice. [PDF]
Nangia-Makker P +8 more
europepmc +1 more source
Metabolic engineering of Escherichia coli BW25113 for the production of Vitamin K<sub>2</sub> based on CRISPR/Cas9 mediated gene knockout and metabolic pathway modification. [PDF]
Ye C +5 more
europepmc +1 more source
Optimization-based framework with flux balance analysis (FBA) and metabolic pathway analysis (MPA) for identifying metabolic objective functions. [PDF]
Wen CM, Papoutsakis E, Ierapetritou M.
europepmc +1 more source
Suggestive Association Between Tryptophan-indole Metabolic Pathway and Total Joint Arthroplasty Early Revision for Heterogeneous Failure Modes in Patients With Primary Osteoarthritis: A Meta-analysis of Metabolomics. [PDF]
Liu M +10 more
europepmc +1 more source

