Results 281 to 290 of about 4,047,137 (345)

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Metabolic pathway modulation by olanzapine: Multitarget approach for treating violent aggression in patients with schizophrenia.

World J Psychiatry
Song YN, Xia S, Sun Z, Chen YC, Jiao L, Wan WH, Zhang HW, Guo X, Guo H, Jia SF, Li XX, Cao SX, Fu LB, Liu MM, Zhou T, Zhang LF, Jia QQ.   +16 more
europepmc   +1 more source

Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to <i>in vitro</i> and <i>in vivo</i> inflammation models. [PDF]

Front Pharmacol
Huang Y, Wang M, Yang Z, Wang X, Wang X, He F.   +5 more
europepmc   +1 more source

Multi‐Scaled Cellulosic Nanonetworks from Tunicates

Advanced Functional Materials, EarlyView.
Microbial and plant nanonetworks of cellulose have enabled a wide range of high‐performance yet sustainable materials. Herein, a third class of cellulosic nanonetworks is showcased by exploiting the only animal tissue‐producing cellulose nanofibers, i.e., ascidians. An ultrastructure including spherical cells and a microvasculature with diameters of 50–
Mano Govindharaj, Mohamed Hamid Salim, M‐Haidar A. Dali, Sarath Haridas Kaniyamparambil, Sagar S. Arya, Zubeen Hathi, Srinivas Mettu, Erlantz Lizundia, Anna Maria Pappa, Charalampos Pitsalidis, Blaise L. Tardy   +10 more
wiley   +1 more source

Integrated Transcriptomics and Metabolomics Reveal Key Genes and Metabolic Pathway in Flower and Fruit Color Formation of <i>Cerasus humilis</i> (Bge.) Sok. [PDF]

Plants (Basel)
Zhang S, Li T, Liu S, Qi X, Yang Y, Zhang J, Jia L, Wang P, Mu X.   +8 more
europepmc   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Metabolic pathway activation and immune microenvironment features in non-small cell lung cancer: insights from single-cell transcriptomics. [PDF]

Front Immunol
Liu Y, Liu H, Xiong Y.
europepmc   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer. [PDF]

Breast Cancer Res
Ma X, Zhang B, Yin X, Yang S, Lin Z, Yang Y, Zhou X.   +6 more
europepmc   +1 more source

Flexible Leaf‐Like Fuel Cell From Plasmonic Janus Nanosheet

Advanced Functional Materials, EarlyView.
A flexible leaf‐like fuel cell is fabricated by conductive gold nanowire sponge‐supported plasmonic Janus nanosheet, which can generate a power of 8.93 mW cm⁻2 with less than 10% performance deterioration even being bent or twisted. Further assembly in a tree‐like layout demonstrates omnidirectional light harvesting capability and wind resistance ...
Yifeng Huang, Qianqian Shi, Siyuan Liu, Wenlong Cheng   +3 more
wiley   +1 more source