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Journal of Pharmaceutical Analysis, 2017 Diets containing high proportions of fruits and vegetables reduce the risk of onset of chronic diseases. The role of herbal medicines in improving human health is gaining popularity over the years, which also increases the need for safety and efficiency ...
B. Ramesh Kumar
doaj +1 more source
Improving clustering with metabolic pathway data [PDF]
, 2014 Background: It is a common practice in bioinformatics to validate each group returned by a clustering algorithm through manual analysis, according to a-priori biological knowledge.
Carrari, Fernando Oscar +4 more
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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 Background The amino acid response (AAR) is an evolutionarily conserved protective mechanism activated by amino acid deficiency through a key kinase, general control nonderepressible 2.
Pu Qin +31 more
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Epigenetics and immunometabolism in diabetes and aging [PDF]
, 2018 Significance: A strong relationship between hyperglycemia, impaired insulin pathway and cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and inflammation.
Cosentino, Francesco, Guzik, Tomasz J.
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Biotechnology for Biofuels, 2017 C2–C4 diols classically derived from fossil resource are very important bulk chemicals which have been used in a wide range of areas, including solvents, fuels, polymers, cosmetics, and pharmaceuticals.
Ye Zhang, Dehua Liu, Zhen Chen
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Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]
, 2012 Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M. +8 more
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Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry [PDF]
, 2011 This work describes a freely available web-based facility which can be used to analyse raw or processed mass spectrometric data from metabolomics experiments and display the metabolites identified – and changes in their experimental abundance – in the ...
Barrett, M.P. +3 more
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Genomic reconstruction of short-chain fatty acid production by the human gut microbiota
Frontiers in Molecular Biosciences, 2022 Short-chain fatty acids (SCFAs) including acetate, formate, propionate, and butyrate are the end products of dietary fiber and host glycan fermentation by the human gut microbiota (HGM).
Maria S. Frolova +4 more
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Lignin engineering in field-grown poplar trees affects the endosphere bacterial microbiome [PDF]
, 2016 Cinnamoyl-CoA reductase (CCR), an enzyme central to the lignin bio-synthetic pathway, represents a promising biotechnological target to reduce lignin levels and to improve the commercial viability of lignocellulosic biomass. However, silencing of the CCR
Beckers, Bram +6 more
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Metabolic Pathways in Alloreactive T Cells [PDF]
Frontiers in Immunology, 2020 Allogeneic hematopoietic stem cell transplantation (aHSCT) is a curative therapy for a range of hematologic illnesses including aplastic anemia, sickle cell disease, immunodeficiency, and high-risk leukemia, but the efficacy of aHSCT is often undermined by graft-versus-host disease (GVHD), where T cells from the donor attack and destroy recipient ...
Craig A. Byersdorfer, Rebecca Brown
openaire +4 more sources