Results 21 to 30 of about 860,607 (312)

Production of C2–C4 diols from renewable bioresources: new metabolic pathways and metabolic engineering strategies

Biotechnology for Biofuels, 2017
C2–C4 diols classically derived from fossil resource are very important bulk chemicals which have been used in a wide range of areas, including solvents, fuels, polymers, cosmetics, and pharmaceuticals.
Ye Zhang, Dehua Liu, Zhen Chen
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Comprehensive Analysis of NAFLD and the Therapeutic Target Identified

Frontiers in Cell and Developmental Biology, 2021
Objective: Non-alcoholic fatty liver disease (NAFLD) is a serious health threat worldwide. The aim of this study was to comprehensively describe the metabolic and immunologic characteristics of NAFLD, and to explore potential therapeutic drug targets for
Weiheng Wen, Peili Wu, Yugang Zhang, Zijian Chen, Jia Sun, Hong Chen   +5 more
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Kinetics and New Mechanism of Azoxystrobin Biodegradation by an Ochrobactrum anthropi Strain SH14

Microorganisms, 2020
Azoxystrobin is one of the most popular strobilurin fungicides, widely used in agricultural fields for decades.Extensive use of azoxystrobin poses a major threat to ecosystems.
Yanmei Feng, Wenping Zhang, Shimei Pang, Ziqiu Lin, Yuming Zhang, Yaohua Huang, Pankaj Bhatt, Shaohua Chen   +7 more
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Metabolic profiling of Apostichopus japonicus body wall exposed to a typical type of PBDEs: potential health risks and impact on sea cucumber health

Frontiers in Marine Science, 2023
IntroductionSea cucumbers are cultivated mainly for their valuable body wall. Polybrominated diphenyl ethers are common persistent pollutants in sea waters with known impacts on aquatic animals nonetheless not yet studied for the body wall of sea ...
Kui Ding, Kui Ding, Kui Ding, Pengji Zhuo, Pengji Zhuo, Meiling Ge, Meiling Ge, Xiaomei Liao, Xiaomei Liao, Jing Mo, Jing Mo, Shilin Liu, Qinzeng Xu, Qinzeng Xu, Xuelei Zhang, Xuelei Zhang   +15 more
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Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

Molecules, 2017
Aberrant metabolism is one of the main driving forces in the initiation and development of ESCC. Both genes and metabolites play important roles in metabolic pathways. Integrative pathway analysis of both genes and metabolites will thus help to interpret
Chunquan Li, Qiuyu Wang, Jiquan Ma, Shengshu Shi, Xin Chen, Haixiu Yang, Junwei Han   +6 more
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The Donor-Dependent and Colon-Region-Dependent Metabolism of (+)-Catechin by Colonic Microbiota in the Simulator of the Human Intestinal Microbial Ecosystem

Molecules, 2021
The intestinal absorption of dietary catechins is quite low, resulting in most of them being metabolized by gut microbiota in the colon. It has been hypothesized that microbiota-derived metabolites may be partly responsible for the association between ...
Qiqiong Li, Florence Van Herreweghen, Marjan De Mey, Geert Goeminne, Tom Van de Wiele   +4 more
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Identification of Metabolic Pathway Systems

Frontiers in Genetics, 2016
The estimation of parameters in even moderately large biological systems is a significant challenge. This challenge is greatly exacerbated if the mathematical formats of appropriate process descriptions are unknown.
Sepideh eDolatshahi, Eberhard Otto Voit
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Effect of Different Dietary Regimes on the Gut Microbiota and Fecal Metabolites of Père David’s Deer

Animals, 2022
A deep understanding of the effect of seasonal dietary changes on the nutrition and health of Père David’s deer in Dafeng Reserve will contribute greatly to Père David’s deer’s protection.
Junai Zhen, Yijun Ren, Huidan Zhang, Xueli Yuan, Libo Wang, Hua Shen, Ping Liu, Yuqing Chen   +7 more
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Corynebacterium diphtheriae Proteome Adaptation to Cell Culture Medium and Serum

Proteomes, 2021
Host-pathogen interactions are often studied in vitro using primary or immortal cell lines. This set-up avoids ethical problems of animal testing and has the additional advantage of lower costs.
Jens Möller, Fatemeh Nosratabadi, Luca Musella, Jörg Hofmann, Andreas Burkovski   +4 more
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Potential Therapies Targeting Metabolic Pathways in Cancer Stem Cells

Cells, 2021
Cancer stem cells (CSCs) are heterogeneous cells with stem cell-like properties that are responsible for therapeutic resistance, recurrence, and metastasis, and are the major cause for cancer treatment failure.
Yao-An Shen, Chang-Cyuan Chen, Bo-Jung Chen, Yu-Ting Wu, Jiun-Ru Juan, Liang-Yun Chen, Yueh-Chun Teng, Yau-Huei Wei   +7 more
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