Results 61 to 70 of about 972,456 (315)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Lipid and Protein Oxidation of Brown Rice and Selenium-Rich Brown Rice during Storage

Foods, 2022
Selenium-rich rice has become one of the effective ways to increase people’s selenium intake. Selenium-containing proteins have higher antioxidant properties, which may lead to selenium-rich brown rice (Se-BR) having better storage stability than ...
Minghui Zhang, Kunlun Liu
doaj   +1 more source

Criação da base de dados Via/Genoma da Chromobacterium violaceum - CvioCyc e análise das informações geradas pelo Software Pathway Tools [PDF]

, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Química.Microrganismos, cujo genoma já foram completamente seqüenciados, como é o caso da Chromobacterium violaceum, possuem ...
Goudel, Artiva Maria
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Metabolic Engineering for the Biosynthesis of Pentalenene in the Rapidly Growing Bacterium Vibrio natriegens

Fermentation
Vibrio natriegens (V. natriegens) is an emerging synthetic biology chassis characterized by rapid growth, and its potential for the synthesis of sesquiterpenes (such as pentalenene) has not been developed.
Lujun Hu, Rui Lin, Hui Jiang, Ge Yao, Jiajia Liu, Penggang Han, Xiukun Wan, Chang Chen, Yunfei Zhang, Shaoheng Bao, Fuli Wang   +10 more
doaj   +1 more source

Comparative Metabolomics Analysis of Cervicitis in Human Patients and a Phenol Mucilage-Induced Rat Model Using Liquid Chromatography Tandem Mass Spectrometry

Frontiers in Pharmacology, 2018
Cervicitis is an exceedingly common gynecological disorder that puts women at high risk of sexually transmitted infections and induces a series of reproductive system diseases.
Xiaoyong Zhang, Junmao Li, Junmao Li, Bin Xie, Bei Wu, Shuangxia Lei, Yun Yao, Mingzhen He, Mingzhen He, Hui Ouyang, Yulin Feng, Yulin Feng, Wen Xu, Shilin Yang, Shilin Yang   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg effect [PDF]

, 2011
The Warburg effect - a classical hallmark of cancer metabolism - is a counter-intuitive phenomenon in which rapidly proliferating cancer cells resort to inefficient ATP production via glycolysis leading to lactate secretion, instead of relying primarily ...
Tomer Shlomi, Eyal Gottlieb, Gottlieb, E., Shlomi, T., Gottlieb Eyal, Roded Sharan, Eytan Ruppin, Ruppin Eytan, Tomer Benyamini, Shlomi Tomer, Sharan Roded, Benyamini Tomer, Ruppin, E., Benyamini, T., Sharan, R.   +14 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Serine biosynthesis with one carbon catabolism represents a novel pathway for ATP generation in cells using alternative glycolysis with zero net ATP production

, 2011
Recent experimental evidence indicates that some cancer cells have an alternative glycolysis pathway with net zero ATP production, implying that upregulation of glycolysis in these cells may not be related to the generation of ATP.
Alexei Vazquez, Zoltan Oltvai, Zoltan N. Oltvai   +2 more
core   +3 more sources