Results 111 to 120 of about 1,443,560 (303)

Technological characterization of vaginal probiotic lactobacilli: resistance to osmotic stress and strains compatibility [PDF]

open access: yes, 2019
Aims: The aim was to evaluate the osmotic stress resistance of vaginal beneficial probiotic strains, their growth kinetics and parameters when growing in salt-added culture media, and their compatibility to go further in the design of a probiotic formula
Birgitt, Wiese   +3 more
core   +1 more source

Sodium metabolism in rat resistance vessels.

open access: yesThe Journal of Physiology, 1983
Using 22Na we have investigated the Na metabolism in rat mesenteric resistance vessels (internal diameter about 200 micron). The intracellular Na content was determined by washing the vessels at 0 degrees C in saline with Li substituted for Na, and was related to smooth muscle volume determined from measurements of media thickness and internal diameter
Aalkjær, Christian, Mulvany, M J
openaire   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The association between Metabolic Syndrome and serum levels of lipid peroxidation and interleukin-6 in Gorgan [PDF]

open access: yes, 2015
Background: There are limited studies on the relationship between inflammatory marker such as IL-6 and lipid peroxidation and metabolic syndrome. Objective: The aim of present study was to assess IL-6 and lipid peroxidation in subjects with and without ...
Khoshnia, M.   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Metabolic risk score indexes validation in overweight healthy people

open access: yes, 2011
The constellation of adverse cardiovascular disease (CVD) and metabolic risk factors, including elevated abdominal obesity, blood pressure (BP), glucose, and triglycerides (TG) and lowered high-density lipoprotein-cholesterol (HDL-C), has been termed the
Benito Peinado, Pedro José   +6 more
core  

Arterial distensibility in adolescents: the influence of adiposity, the metabolic syndrome, and classic risk factors. [PDF]

open access: yes, 2005
BACKGROUND: Atherosclerosis develops from childhood, but the determinants of this preclinical stage remain uncertain. We examined the relations of classic coronary risk factors, adiposity and its associated metabolic disturbances, to arterial ...
Cook, DG   +6 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Negative cross-resistance to chlorfenapyr in pyrethroid-resistance house flies

open access: yesРоссийский паразитологический журнал
The purpose of the research is to evaluate the susceptibility to deltamethrin and the pro-insecticide chlorfenapyr in a field population of Musca domestica L.
E. A. Silivanova   +6 more
doaj   +1 more source

Metabolic syndrome and insulin resistance in obese adolescents

open access: yesRevista Paulista de Pediatria, 2014
Objective: To verify the prevalence of metabolic syndrome and insulin resistance in obese adolescents and its relationship with different body composition indicators.
Amanda Oliva Gobato   +4 more
doaj   +1 more source

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