Results 11 to 20 of about 5,645,921 (292)

Metabolic Resistance in Bed Bugs [PDF]

open access: yesInsects, 2011
Blood-feeding insects have evolved resistance to various insecticides (organochlorines, pyrethroids, carbamates, etc.) through gene mutations and increased metabolism. Bed bugs (Cimex lectularius) are hematophagous ectoparasites that are poised to become
Omprakash Mittapalli   +2 more
doaj   +5 more sources

Metabolic checkpoint of ferroptosis resistance [PDF]

open access: yesMolecular & Cellular Oncology, 2021
The metabolic checkpoint of ferroptosis remains obscure. We find that glucose favors system xc− inhibitor-induced ferroptosis by activating pyruvate oxidation, thereby promoting fatty acid synthesis and subsequent lipid peroxidation.
Jiao Liu, Rui Kang, Daolin Tang
doaj   +3 more sources

Metabolic Plasticity in Chemotherapy Resistance [PDF]

open access: yesFrontiers in Oncology, 2020
Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death. Thus, new strategies to deal with the evasion of drug response and to improve clinical outcomes are needed.
Maria Andrea Desbats   +5 more
doaj   +3 more sources

Metabolic mechanisms of immunotherapy resistance [PDF]

open access: yesExploration of Targeted Anti-tumor Therapy
Immunotherapy has revolutionized cancer treatment, yet its efficacy is frequently compromised by metabolic mechanisms that drive resistance. Understanding how tumor metabolism shapes the immune microenvironment is essential for developing effective ...
Luis Cabezón-Gutiérrez   +4 more
doaj   +3 more sources

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector Anopheles funestus but PBO-Based Olyset Plus Net Remains Effective

open access: yesPathogens, 2022
Malaria remains a major public health concern in Africa. Metabolic resistance in major malaria vectors such as An. funestus is jeopardizing the effectiveness of long-lasting insecticidal nets (LLINs) to control malaria.
Benjamin D. Menze   +5 more
doaj   +1 more source

Metabolic resistance to acetolactate synthase-inhibitors in Beckmannia syzigachne: Identification of CYP81Q32 and its transcription regulation.

open access: yesThe Plant Journal, 2023
Frequent herbicide use selects for herbicide resistance in weeds. Cytochrome P450s are important detoxification enzymes responsible for herbicide resistance in plants.
Junzhi Wang   +7 more
semanticscholar   +1 more source

First Report of the Molecular Mechanism of Resistance to Tribenuron-Methyl in Silene conoidea L.

open access: yesPlants, 2022
Silene conoidea L. is an annual troublesome broadleaf weed in winter wheat fields in China. In recent years, field applications of tribenuron-methyl have been ineffective in controlling S. conoidea in Hebei Province, China.
Ying Sun   +7 more
doaj   +1 more source

PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis.

open access: yesCell Reports, 2021
Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of ferroptotic death remains poorly elucidated.
Xinxin Song   +8 more
semanticscholar   +1 more source

Esterase, Glutathione S-Transferase and NADPH-Cytochrome P450 Reductase Activity Evaluation in Cacopsylla pyri L. (Hemiptera: Psyllidae) Individual Adults

open access: yesInsects, 2021
Cacopsylla pyri (L.) (Hemiptera: Psyllidae) is a key pest of pear orchards in Spain. The large number of insecticide treatments necessary for control may be an important contributor to the emergence of resistance.
Dolors Bosch-Serra   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy