Results 11 to 20 of about 873,593 (157)
Metabolic checkpoint of ferroptosis resistance [PDF]
Molecular & Cellular Oncology, 2021 The metabolic checkpoint of ferroptosis remains obscure. We find that glucose favors system xc− inhibitor-induced ferroptosis by activating pyruvate oxidation, thereby promoting fatty acid synthesis and subsequent lipid peroxidation.
Jiao Liu, Rui Kang, Daolin Tang
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Metabolic Plasticity in Chemotherapy Resistance [PDF]
Frontiers in Oncology, 2020 Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death. Thus, new strategies to deal with the evasion of drug response and to improve clinical outcomes are needed.
Maria Andrea Desbats +5 more
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Metabolic mechanisms of immunotherapy resistance [PDF]
Exploration of Targeted Anti-tumor TherapyImmunotherapy has revolutionized cancer treatment, yet its efficacy is frequently compromised by metabolic mechanisms that drive resistance. Understanding how tumor metabolism shapes the immune microenvironment is essential for developing effective ...
Luis Cabezón-Gutiérrez +4 more
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Metabolic regulation of antibiotic resistance [PDF]
FEMS Microbiology Reviews, 2011 It is generally assumed that antibiotics and resistance determinants are the task forces of a biological warfare in which each resistance determinant counteracts the activity of a specific antibiotic. According to this view, antibiotic resistance might be considered as a specific response to an injury, not necessarily linked to bacterial metabolism ...
Martínez, José L., Rojo, Fernando
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Plants, 2022 In crop fields, resistance to acetolactate synthase (ALS)-inhibiting herbicides found in many troublesome weed species, including Bromus japonicus Thunb, is a worldwide problem. In particular, the development of herbicide resistance in B.
Yuning Lan +7 more
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From Global to Local—New Insights into Features of Pyrethroid Detoxification in Vector Mosquitoes
Insects, 2021 The threat of mosquito-borne diseases continues to be a problem for public health in subtropical and tropical regions of the world; in response, there has been increased use of adulticidal insecticides, such as pyrethroids, in human habitation areas over
William C. Black +4 more
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Julius-Kühn-Archiv, 2022 The herbicide flufenacet, applied in pre-emergence, acts as an inhibitor of the synthesis of very long-chain fatty acids (HRAC group 15) and is an important component in the control of grasses in winter cereals, especially when resistance to other ...
Parcharidou. Evlampia +2 more
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Memorias do Instituto Oswaldo Cruz, 2012 The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance.
Isabela Reis Montella +2 more
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Model for metabolic resistance against ALS inhibitors
Julius-Kühn-Archiv, 2014 Due to herbicide selection pressure metabolic resistance has evolved in many weed species. In this paper we analyse the interaction between the branched chain amino acid (BBC) pathway and detoxifying pathways for herbicide breakdown.
Richter, Otto +2 more
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Agronomy, 2023 The metabolic resistance of plants to herbicides is similar to the herbicide metabolism process accelerated by safeners. The tolerance to fenoxaprop-P-ethyl (FE) is distinct among different varieties of rice in which phytotoxicity forms easily, resulting
Yaning Zhao +6 more
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