Results 41 to 50 of about 5,645,921 (292)

Metabolic syndrome and insulin resistance in migraine [PDF]

open access: yesThe Journal of Headache and Pain, 2012
Metabolic syndrome is associated with migraine but there is no study comparing the characteristics of migraine with and without metabolic syndrome from Southeast Asia. This study was therefore undertaken to compare the clinical characteristics of migraine in patients with and without metabolic syndrome and insulin resistance.
Bhoi, Sanjeev K.   +2 more
openaire   +2 more sources

ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer

open access: yesJournal of experimental & clinical cancer research : CR, 2021
Acquired resistance of 5-fluorouracil (5-FU) remains a clinical challenge in colorectal cancer (CRC), and efforts to develop targeted agents to reduce resistance have not yielded success.
S. Dong   +12 more
semanticscholar   +1 more source

Lipid Metabolism and Resistance to Anticancer Treatment [PDF]

open access: yesBiology, 2020
Metabolic reprogramming is crucial to respond to cancer cell requirements during tumor development. In the last decade, metabolic alterations have been shown to modulate cancer cells’ sensitivity to chemotherapeutic agents including conventional and targeted therapies.
Germain, Nicolas   +5 more
openaire   +4 more sources

Cytochrome P450s-Involved Enhanced Metabolism Contributes to the High Level of Nicosulfuron Resistance in Digitaria sanguinalis from China

open access: yesBiology, 2023
Large crabgrass (Digitaria sanguinalis (L.) Scop.) is one of the major malignant grass weeds in Chinese maize (Zea mays L.) fields, and it has recently developed resistance to the acetolactate synthase (ALS)-inhibiting herbicide nicosulfuron.
Xumiao Wang   +6 more
doaj   +1 more source

Clinically relevant mutations in core metabolic genes confer antibiotic resistance

open access: yesScience, 2021
The many roads to resistance Antibiotic resistance arising from mutation is common among pathogenic bacteria. However, this process is not well understood, and most of the mutations that have been identified to confer resistance do so by modification of ...
A. Lopatkin   +9 more
semanticscholar   +1 more source

Fructose, insulin resistance, and metabolic dyslipidemia [PDF]

open access: yesNutrition & Metabolism, 2005
Abstract Obesity and type 2 diabetes are occurring at epidemic rates in the United States and many parts of the world. The "obesity epidemic" appears to have emerged largely from changes in our diet and reduced physical activity. An important but not well-appreciated dietary change has been the substantial increase in the amount of dietary ...
Basciano, Heather   +2 more
openaire   +4 more sources

The Role of Tumour Metabolism in Cisplatin Resistance [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
Cisplatin is a chemotherapy drug commonly used in cancer treatment. Tumour cells are more sensitive to cisplatin than normal cells. Cisplatin exerts an antitumour effect by interfering with DNA replication and transcription processes. However, the drug-resistance properties of tumour cells often cause loss of cisplatin efficacy and failure of ...
Lude Wang   +4 more
openaire   +3 more sources

Target-site and metabolic resistance mechanisms to penoxsulam in barnyardgrass (Echinochloa crus-galli (L.) P. Beauv).

open access: yesJournal of Agricultural and Food Chemistry, 2019
Herbicide resistance identification is essential for effective chemical weed control. This study quantified the differences in growth response between penoxsulam resistant (R) and sensitive (S) Echinochloa crus-galli populations, explored the changes in ...
Jiapeng Fang   +5 more
semanticscholar   +1 more source

Evaluation of Insecticides induced hormesis on the demographic parameters of Myzus persicae and expression changes of metabolic resistance detoxification genes

open access: yesScientific Reports, 2018
Insecticide induced-hormesis is a bi-phasic phenomenon generally characterized by low-dose induction and high-dose inhibition. It has been linked to insect pest outbreaks and insecticide resistance, which have importance in the integrated pest management
M. U. Sial   +5 more
semanticscholar   +1 more source

Pyroptosis and Insulin Resistance in Metabolic Organs

open access: yesInternational Journal of Molecular Sciences, 2022
Skeletal muscle serves as the optimal effective organ to balance glucose homeostasis, but insulin resistance (IR) in skeletal muscle breaks this balance by impeding glucose uptake and causes metabolic disorders. IR in skeletal muscle is caused by multiple factors, and it has been reported that systemic low-grade inflammation is related to skeletal ...
Huiting Wei, Di Cui
openaire   +2 more sources

Home - About - Disclaimer - Privacy