Results 31 to 40 of about 5,645,921 (292)
Cancer Metabolism and Drug Resistance [PDF]
Metabolites, 2015 Metabolic alterations, driven by genetic and epigenetic factors, have long been known to be associated with the etiology of cancer. Furthermore, accumulating evidence suggest that cancer metabolism is intimately linked to drug resistance, which is currently one of the most important challenges in cancer treatment. Altered metabolic pathways help cancer
Mahbuba Rahman, Mohammad Rubayet Hasan
openaire +3 more sources
Dinitroaniline Herbicide Resistance and Mechanisms in Weeds
Frontiers in Plant Science, 2021 Dinitroanilines are microtubule inhibitors, targeting tubulin proteins in plants and protists. Dinitroaniline herbicides, such as trifluralin, pendimethalin and oryzalin, have been used as pre-emergence herbicides for weed control for decades.
Jinyi Chen +5 more
doaj +1 more source
Metabolic flexibility and insulin resistance
American Journal of Physiology-Endocrinology and Metabolism, 2008 Metabolic flexibility is the capacity for the organism to adapt fuel oxidation to fuel availability. The inability to modify fuel oxidation in response to changes in nutrient availability has been implicated in the accumulation of intramyocellular lipid and insulin resistance.
Galgani Fuentes, José +2 more
openaire +4 more sources
Insecticide resistance in mosquitoes: Development, mechanisms and monitoring
Ceylon Journal of Science, 2018 Mosquito-borne diseases are of major public health concerns, mainly in tropical countries. Control of these diseases is primarily achieved through mosquito control. One of the major challenges encountered by mosquito control programmes is the development
S. H. P. P. Karunaratne +3 more
doaj +1 more source
Biology, 2022 Pyrethroids are widely applied insecticides in agriculture, but their frequent use has provoked many cases of resistance, in which mutations in the voltage-gated sodium channel (VGSC), the pyrethroid target-site, were shown to play a major role. However,
Berdien De Beer +5 more
doaj +1 more source
The crucial role and mechanism of insulin resistance in metabolic disease
Frontiers in Endocrinology, 2023 Insulin resistance (IR) plays a crucial role in the development and progression of metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty liver disease, and provides the basis for a common understanding of these ...
Xuefei Zhao +5 more
semanticscholar +1 more source
Julius-Kühn-Archiv, 2022 Die Bekämpfung von Ackerfuchsschwanz (Alopecurus myosuroides Huds.) stellt vor dem Hintergrund der zunehmenden Resistenzen eine Herausforderung dar.
Wagner, Jean, Mücke, Manuela
doaj +1 more source
Cholesterol metabolism and resistance to tamoxifen
Current Opinion in Pharmacology, 2012 The oncoprotein MUC-1 was shown to upregulate the transcription of genes encoding cholesterol and lipid metabolic enzymes and correlated with a resistance to Tamoxifen (Tam) despite the presence of estrogen receptor α in breast cancer tumors. The importance of this observation is supported by molecular studies on Tam suggesting two additional ...
Poirot, Marc +2 more
openaire +2 more sources
Origin, mechanism and molecular basis of weed resistance to herbicides
Plant Protection Science, 2004 This review summarises information from the literature and experimental experience of the authors in research on weed resistance to herbicides. Factors conditioning the origin of resistance are described.
Daniela Chodová +3 more
doaj +1 more source
Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy
Pathogens, 2021 Monitoring cases of insecticide resistance aggravation and the effect on the efficacy of control tools is crucial for successful malaria control. In this study, the resistance intensity of major malaria vectors from Uganda was characterised and its ...
Magellan Tchouakui +7 more
doaj +1 more source