Results 51 to 60 of about 5,645,921 (292)

Investigation of the influence of a glutathione S-transferase metabolic resistance to pyrethroids/DDT on mating competitiveness in males of the African malaria vector, Anopheles funestus

Wellcome Open Research, 2019
Background: Metabolic resistance is a serious challenge to current insecticide-based interventions. The extent to which it affects natural populations of mosquitoes including their reproduction ability remains uncharacterised.
Magellan Tchouakui, Billy Tene Fossog, Brigitte Vanessa Ngannang, Doumani Djonabaye, Williams Tchapga, F. Njiokou, C. Wondji   +6 more
semanticscholar   +1 more source

Angiogenesis and Metabolism: Entwined for Therapy Resistance [PDF]

Trends in Cancer, 2017
Angiogenesis and metabolism are entwined processes that permit tumor growth and progression. Blood vessel supply is necessary for tumor survival not only by providing oxygen and nutrients for anabolism but also by removing waste products from cellular metabolism.
Gabriela Jiménez-Valerio, Oriol Casanovas   +1 more
openaire   +4 more sources

Sulfasalazine colon-specific drug delivery by selenium nanoparticle

Journal of Trace Elements and Minerals, 2022
Background: The goal was to assess the specific colon delivery and investigation of synergistic anti-inflammatory effects of the selenium nanoparticle (SeNPs) as a bioactive carrier for oral administration.
Alireza Hashemzadeh, Fereshteh Asgharzadeh, Atieh Yaghoubi, Seyedeh Elnaz Nazari, Seyed Mahdi Hassanian, Amir Avan, Majid Rezaei, Saman Soleimanpour, Majid Khazaei   +8 more
doaj   +1 more source

In the hunt for genomic markers of metabolic resistance to pyrethroids in the mosquito Aedes aegypti: An integrated next-generation sequencing approach

PLoS Neglected Tropical Diseases, 2017
Background The capacity of Aedes mosquitoes to resist chemical insecticides threatens the control of major arbovirus diseases worldwide. Until alternative control tools are widely deployed, monitoring insecticide resistance levels and identifying ...
Frédéric Faucon, T. Gaude, I. Dusfour, V. Navratil, V. Corbel, W. Juntarajumnong, R. Girod, R. Poupardin, F. Boyer, S. Reynaud, J. David   +10 more
semanticscholar   +1 more source

AMPK, insulin resistance, and the metabolic syndrome [PDF]

Journal of Clinical Investigation, 2013
Insulin resistance (IR) and hyperinsulinemia are hallmarks of the metabolic syndrome, as are central adiposity, dyslipidemia, and a predisposition to type 2 diabetes, atherosclerotic cardiovascular disease, hypertension, and certain cancers. Regular exercise and calorie restriction have long been known to increase insulin sensitivity and decrease the ...
Neil B, Ruderman, David, Carling, Marc, Prentki, José M, Cacicedo   +3 more
openaire   +2 more sources

Insecticide Resistance Mutations, Enzymatic Activity, and Pathogen Infection in Culex quinquefasciatus from Haiti

Insects
Haiti is a Caribbean country of about 11 million people with a high burden of mosquito-transmitted disease and limited vector control, thereby making effective operational mosquito control of high importance.
Primrose Tanachaiwiwat, Neil D. Sanscrainte, Bernard A. Okech, Alden S. Estep   +3 more
doaj   +1 more source

Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control

PLoS Genetics, 2017
Insecticide resistance in mosquito populations threatens recent successes in malaria prevention. Elucidating patterns of genetic structure in malaria vectors to predict the speed and direction of the spread of resistance is essential to get ahead of the ‘
K. Barnes, Gareth D. Weedall, Miranda Ndula, H. Irving, Themba Mzihalowa, J. Hemingway, C. Wondji   +6 more
semanticscholar   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Unraveling the Transcriptional Basis of Temperature-Dependent Pinoxaden Resistance in Brachypodium hybridum

Frontiers in Plant Science, 2017
Climate change endangers food security and our ability to feed the ever-increasing human population. Weeds are the most important biotic stress, reducing crop-plant productivity worldwide.
Maor Matzrafi, Lidor Shaar-Moshe, Baruch Rubin, Zvi Peleg   +3 more
doaj   +1 more source

Fitness Costs of the Glutathione S-Transferase Epsilon 2 (L119F-GSTe2) Mediated Metabolic Resistance to Insecticides in the Major African Malaria Vector Anopheles Funestus

Genes, 2018
Metabolic resistance to insecticides threatens malaria control. However, little is known about its fitness cost in field populations of malaria vectors, thus limiting the design of suitable resistance management strategies.
Magellan Tchouakui, Jacob M. Riveron, Doumani Djonabaye, Williams Tchapga, H. Irving, Patrice Soh Takam, F. Njiokou, C. Wondji   +7 more
semanticscholar   +1 more source