Results 71 to 80 of about 3,890,227 (163)

Drug Resistance: The Role of Sphingolipid Metabolism

open access: yesInternational Journal of Molecular Sciences
A significant challenge in cancer treatment is the rising problem of drug resistance that reduces the effectiveness of therapeutic strategies. Current knowledge shows that multiple mechanisms play a role in cancer drug resistance. Another mechanism that has gained attention is the alteration in sphingolipid trafficking and the dysregulation of its ...
Assem Zhakupova   +4 more
openaire   +2 more sources

Metabolic enzyme(s) confer imidacloprid resistance in a clone of Myzus persicae (Sulzer) (Hemiptera: Aphididae) from Greece

open access: yes, 2010
BACKGROUND: Previous studies have reported varying levels of resistance against imidacloprid in several insect species, including populations of the peach-potato aphid, Myzus persicae (Sulzer).
Field, L. M.   +5 more
core   +1 more source

Metabolic link between Insulin Resistance and Obesity: Novel Drug candidates

open access: yes, 2023
This research report comprehensively investigates the intricate link between insulin resistance and obesity, addressing shared risk factors and emphasizing the importance of a combined approach involving lifestyle modifications and pharmacological ...
Khokhar, Multazam Ali
core  

Metabolic Syndrome Criteria As Predictors of Insulin Resistance, Inflammation and Mortality in Chronic Hemodialysis Patients

open access: yes, 2014
Background: Chronic kidney disease (CKD) and metabolic syndrome are characterized by overlapping disorders, including glucose intolerance, hypertension, dyslipidemia, and, in some cases, obesity.
Minicucci, Marcos Ferreira [UNESP]   +11 more
core   +1 more source

A dietary interventional study moderating fat intake in Saudi subjects with metabolic disease [PDF]

open access: yes
The gut-derived bacteria, endotoxin (lipopolysaccharide), have been observed to be raised in patients with type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) which appears to represent a source of diet induced inflammation exacerbating ...
Aldesi, Darh Assad D.
core  

Metabolic Reprogramming Through Polyphenol Networks: A Systems Approach to Metabolic Inflammation and Insulin Resistance

open access: yes
Obesity-induced insulin resistance and type 2 diabetes mellitus (T2DM) represent complex systemic disorders marked by chronic inflammation, oxidative stress, mitochondrial dysfunction, and endoplasmic reticulum (ER) stress.
Akter, Shamima   +27 more
core   +1 more source

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