Results 101 to 110 of about 5,150,728 (333)

Metabolic Reprogramming is a Hallmark of Metabolism Itself [PDF]

BioEssays, 2020
AbstractThe reprogramming of metabolism has been identified as one of the hallmarks of cancer. It is becoming more and more frequent to connect other diseases with metabolic reprogramming. This article aims to argue that metabolic reprogramming is not driven by disease but instead is the main hallmark of metabolism, based on its dynamic behavior that ...
openaire   +5 more sources

Insulin Requirement Profiles of Short-Term Continuous Subcutaneous Insulin Infusion Therapy in Patients With Type 2 Diabetic Nephropathy

International Journal of Endocrinology
Conclusion: In patients with T2DKD who received short-term CSII therapy, the insulin requirement decline with the decrease of eGFR, while the %TBa did not change significantly.
Qianqiu Feng, Biyun Li, Jiating Lin, Li Zou, Wen Xu, Longyi Zeng, Ping Li, Shuo Lin   +7 more
doaj   +1 more source

A Study on Weight Loss Cause as per the Side Effect of Liraglutide

Cardiovascular Therapeutics, 2022
Purpose. Liraglutide is known to have much lower weight loss effects in real clinical fields than in randomized clinical trials because of its side effects (SE) and discomfort associated with injections.
Jin Yu, Jeongmin Lee, Seung-Hwan Lee, Jae-Hyung Cho, Hun-Sung Kim   +4 more
doaj   +1 more source

Contribution of phenylpropanoid metabolism to plant development and plant-environment interactions.

Journal of Integrative Plant Biology, 2020
Phenylpropanoid metabolism is one of the most important metabolisms in plants, yielding more than 8,000 metabolites contributing to plant development and plant-environment interplay.
Nai-Qian Dong, Hong-Xuan Lin
semanticscholar   +1 more source

Evaluation of Compliance With International Guidelines During the Follow-Up of Hypoparathyroidism

International Journal of Endocrinology
Conclusion: In our research, it was discovered that patients with hypoparathyroidism had low compliance rates with the guidelines. We believe that the cause of this is the inability to provide the patients with enough time in intense polyclinic ...
Beril Turan Erdogan, Sefika Burcak Polat, Caglar Keskin, Narin Nasiroglu İmga, Didem Ozdemir, Oya Topaloglu, Reyhan Ersoy, Bekir Cakir   +7 more
doaj   +1 more source

Extracellular Vesicles Derived from Three-Dimensional-Cultured Human Umbilical Cord Blood Mesenchymal Stem Cells Prevent Inflammation and Dedifferentiation in Pancreatic Islets

Stem Cells International, 2023
It is unclear whether extracellular vesicles (EVs) from mesenchymal stem cells (MSCs) have a direct protective effect on pancreatic islets. In addition, whether culturing MSCs in three dimensions (3D) instead of a monolayer (2D) can induce changes in the
Eunwon Lee, Seungyeon Ha, Gyuri Kim, Jae Hyeon Kim, Sang-Man Jin   +4 more
doaj   +1 more source

Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.

New England Journal of Medicine, 2013
BACKGROUND Recent studies in animals have shown a mechanistic link between intestinal microbial metabolism of the choline moiety in dietary phosphatidylcholine (lecithin) and coronary artery disease through the production of a proatherosclerotic ...
W. Tang, Zeneng Wang, B. Levison, Robert A. Koeth, Earl B. Britt, Xiaoming Fu, Yuping Wu, S. Hazen   +7 more
semanticscholar   +1 more source

Metabolic reprogramming promotes myogenesis during aging [PDF]

, 2019
Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Belli, R, Bonato, A, Caruso, M, Costelli, P, De Angelis, L, Ferraro, E., Leigheb, M, Mirabilii, S, Molfino, A, Muscaritoli, M, Ricciardi, Mr, Tafuri, A   +11 more
core   +3 more sources

A Multicenter, Randomized, Open-Label Study to Compare the Effects of Gemigliptin Add-on or Escalation of Metformin Dose on Glycemic Control and Safety in Patients with Inadequately Controlled Type 2 Diabetes Mellitus Treated with Metformin and SGLT-2 Inhibitors (SO GOOD Study)

Journal of Diabetes Research
Background. We aimed to compare efficacy and safety between gemigliptin add-on and escalation of the metformin dose in patients with inadequately controlled type 2 diabetes mellitus (T2DM) despite treatment with metformin and SGLT2 inhibitors.
Hae Jin Kim, Jung Hyun Noh, Min Kyong Moon, Sung Hee Choi, Seung-Hyun Ko, Eun-Jung Rhee, Kyu Yeon Hur, In-Kyung Jeong   +7 more
doaj   +1 more source

Lipid Metabolism

, 2016
Perilipin 2, also known as Adipose differentiation-relation protein or PLIN2, is a lipid droplet-binding protein present in almost every tissue. The absence of PLIN2 upregulates hepatic very low-density lipoprotein secretion, relieves hepatosteatosis ...
Chan, DSc, MBBS, Lawrence, Chen, Elaine, Moore, Paige   +2 more
core