Results 101 to 110 of about 2,371,969 (318)

Drug metabolism‐related eight‐gene signature can predict the prognosis of gastric adenocarcinoma [PDF]

, 2021
Hongmei Yin, Qiong He, Jia Chen, Zhen Li, Wanli Yang, Xiaobo Hu   +5 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Severe Hypercalcemia and Confusion in a Middle-Aged Male: The Hidden Diagnosis of Parathyroid Carcinoma

Case Reports in Endocrinology
Parathyroid cancer (PC) is one of the rarest causes of primary hyperparathyroidism (PHPT), typically exhibiting an indolent course but presenting with more severe symptoms compared to its benign counterparts.
Helena Fahmi, Mahmoud Karaki, Fatima Yasmin, Layal Akl, Paola Atallah   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Retracted: Ghanaians Might Be at Risk of Inadequate Dietary Intake of Potassium

Journal of Nutrition and Metabolism, 2017
Journal of Nutrition and Metabolism
doaj   +1 more source

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

, 2013
Isaline Rowe, Marco Chiaravalli, Valeria Mannella, Valeria Ulisse, Giacomo Quilici, Monika Pema, Xuewen Song, Hangxue Xu, Silvia Mari, Feng Qian, York Pei, Giovanna Musco, Alessandra Boletta   +12 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Physiological significance of altered insulin metabolism in the conscious rat during lactation [PDF]

, 1984
Richard Jones, Vesna Ilić, D H Williamson   +2 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Resolving the central metabolism of Arabidopsis guard cells [PDF]

, 2017
Semidán Robaina‐Estévez, Danilo M. Daloso, Youjun Zhang, Alisdair R. Fernie, Zoran Nikoloski   +4 more
openalex   +1 more source