Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. [PDF]
, 2016 Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer.
Anderton, Brittany +11 more
core +1 more source
A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output [PDF]
, 2015 Aerobic exercise, in spite of its multi-organ benefit and potent effect on the metabolome, has yet to be investigated comprehensively via an untargeted metabolomics technology.
Anthony, Nahoum +5 more
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Formation of biologically active benzodiazepine metabolites in Arabidopsis thaliana cell cultures and vegetable plants under hydroponic conditions. [PDF]
, 2019 The use of recycled water for agricultural irrigation comes with the concern of exposure to crops by contaminants of emerging concerns (CECs). The concentration of CECs in plant tissues will depend on uptake, translocation and metabolism in plants ...
Dudley, Stacia +4 more
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Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication [PDF]
, 2010 Background Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the
Castorena, Kathryn M +2 more
core +4 more sources
The Journal of Headache and Pain, 2015 Background In the past decade, several studies have shown a significant association between migraine and several features of the metabolic syndrome (MetS), including insulin resistance, systemic hypertension, and obesity. In addition, headache is a highly prevalent symptom in several metabolic disorders. The purpose of this review was to discuss recent
openaire +4 more sources
Tryptophan metabolism in health and disease.
Cell Metabolism, 2023 Chen Xue +10 more
semanticscholar +1 more source
Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. [PDF]
, 2019 Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like ...
de Oliveira, Patricia Gnieslaw +4 more
core +1 more source
Correlation of qEEG with PET in schizophrenia [PDF]
, 1998 PET relative metabolism was correlated with quantitative EEG in 9 schizophrenic patients. The PET metabolic regions of interest were the frontal lobes, thalamus and basal ganglia, and right and left temporal lobes.
Alper, Kenneth +4 more
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Metabolism disrupting chemicals and metabolic disorders
Reproductive Toxicology, 2017 The recent epidemics of metabolic diseases, obesity, type 2 diabetes(T2D), liver lipid disorders and metabolic syndrome have largely been attributed to genetic background and changes in diet, exercise and aging. However, there is now considerable evidence that other environmental factors may contribute to the rapid increase in the incidence of these ...
Heindel, Jerrold J +11 more
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Journal of Diabetes ResearchConclusion: Oxidative stress indices are associated with HTN status and correlated with uncontrolled HTN in populations with T2D.
Seyed Arsalan Seyedi +11 more
doaj +1 more source