Results 61 to 70 of about 5,150,728 (333)

Metabolic networks are almost nonfractal: A comprehensive evaluation [PDF]

open access: yesPhys. Rev. E 90, 022802 (2014), 2014
Network self-similarity or fractality are widely accepted as an important topological property of metabolic networks; however, recent studies cast doubt on the reality of self-similarity in the networks. Therefore, we perform a comprehensive evaluation of metabolic network fractality using a box-covering method with an earlier version and the latest ...
arxiv   +1 more source

Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance.

open access: yesNutrition reviews, 2009
Polyphenols constitute one of the most numerous and ubiquitous groups of plant metabolites and are an integral part of both human and animal diets. Ranging from simple phenolic molecules to highly polymerized compounds with molecular weights of greater ...
L. Bravo
semanticscholar   +1 more source

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]

open access: yes, 2017
Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y   +12 more
core   +1 more source

Targeting cancer metabolism in the era of precision oncology

open access: yesNature reviews. Drug discovery, 2021
One hundred years have passed since Warburg discovered alterations in cancer metabolism, more than 70 years since Sidney Farber introduced anti-folates that transformed the treatment of childhood leukaemia, and 20 years since metabolism was linked to ...
Zachary E. Stine   +3 more
semanticscholar   +1 more source

Neuroendocrine Regulation of Metabolism [PDF]

open access: yes, 2016
Given the current environment in most developed countries, it is a challenge to maintain a good balance between calories consumed and calories burned, although maintenance of metabolic balance is key to good health. Therefore, understanding how metabolic
Becu Villalobos, D.   +5 more
core   +3 more sources

Data, information, knowledge and principle: back to metabolism in KEGG

open access: yesNucleic Acids Res., 2013
In the hierarchy of data, information and knowledge, computational methods play a major role in the initial processing of data to extract information, but they alone become less effective to compile knowledge from information.
M. Kanehisa   +5 more
semanticscholar   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

Induction of PEP Carboxylase and Crassulacean Acid Metabolism by Gibberellic Acid in Mesembryanthemum crystallinum [PDF]

open access: yes, 2001
The induction of Crassulacean acid metabolism in Mesembryanthemum crystallinum was investigated in response to foliar application of gibberellic acid (GA).
Earnest, Jeannine   +5 more
core   +2 more sources

Diabetes Mellitus Type 2 Patients with Abdominal Obesity Are Prone to Osteodysfunction: A Cross-Sectional Study

open access: yesJournal of Diabetes Research, 2023
Introduction. The interaction between diabetes, obesity, and bone metabolism was drawing increasing public attention. However, the osteometabolic changes in diabetes mellitus type 2 (T2DM) patients with abdominal obesity have not been fully revealed ...
Hui Guo   +11 more
doaj   +1 more source

Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents [PDF]

open access: yes, 2017
peer-reviewedThe gut hormone glucagon-like peptide (GLP)-1 and its analogues represent a new generation of anti-diabetic drugs, which have also demonstrated propensity to modulate host lipid metabolism.
Cryan, John F.   +13 more
core   +4 more sources

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